Overview
- Offers a unique perspective on the pathogenesis and immunological dynamic of dermatological conditions
- Intends to gather information on the functional significance of data provided by genome-wide associations
- Gives the readers ideas for designing new targeted treatments
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1367)
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Table of contents (18 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Immunogenetic investigations have made targeted treatment strategies possible for diseases such as psoriasis and pemphigus. Even though these strategies have revolutionized the management of chronic dermatological conditions such as psoriasis, still there are a lot of unanswered questions. For instance, psoriasis patients respond very differently to each of the commercially available biological agents. This diversity could be partially explained by the differences in the sets of genes responsible for disease induction in each individual. Thus whole genome sequencing strategies, if feasible at individual levels, might help in tailoring these targeted treatments based on specific genetic backgrounds.
Our intention in preparing this book was to explore the broad spectrum of the genetic aspects of immunological processes involved in cutaneous diseases. We have tried to cover most areas of dermatology where enough studies were available to gather a chapter. Still, there is a substantial lack of knowledge on the immunogenetics of many dermatological conditions. We hope that this book would encourage the investigators to fill these gaps of knowledge.
Editors and Affiliations
About the editors
Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the founding President of Universal Scientific Education and Research Network (USERN). Prof. Rezaei has already been the Director of more than 50 research projects and has designed and participated in several international collaborative projects. Prof. Rezaei is an editorial assistant or board member for more than 30 international journals. He has edited more than 30 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,000 scientific papers in the international journals.
Fateme Rajabi is a board-certified dermatologist. She gained her medical degree from Tehran University of Medical Sciences in 2014 and subsequently attended a dermatology residency at Shahid Beheshti University of Medical Sciences. She is currently affiliated with the Center for Research & Training in Skin Diseases & Leprosy, Tehran University of Medical Sciences, and manages several research committees including the Network of Dermatological Research (NDR) an interest group of Universal Scientific Education and Research Network (USERN).
Bibliographic Information
Book Title: The Immunogenetics of Dermatologic Diseases
Editors: Nima Rezaei, Fateme Rajabi
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-030-92616-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-030-92615-1Published: 15 March 2022
Softcover ISBN: 978-3-030-92618-2Published: 16 March 2023
eBook ISBN: 978-3-030-92616-8Published: 14 March 2022
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XXI, 450
Number of Illustrations: 2 b/w illustrations, 62 illustrations in colour
Topics: Cancer Research, Human Genetics, Immunology, Molecular Medicine, Dermatology