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TRP Channels in Drug Discovery

Volume I

  • Arpad Szallasi
  • Tamás Bíró

Part of the Methods in Pharmacology and Toxicology book series (MIPT)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Introduction

  3. TRP Channels, from A1 to V4

    1. Front Matter
      Pages 41-41
    2. Jun Chen, Steve McGaraughty, Philip R. Kym
      Pages 43-59
    3. Barbara A. Miller
      Pages 89-102
    4. Barbara Colsoul, Miklos Kecskes, Koenraad Philippaert, Aurelie Menigoz, Rudi Vennekens
      Pages 103-125
    5. Vladimir Chubanov, Jonathan T. Eggenschwiler, Lillia V. Ryazanova, Thomas Gudermann, Alexey G. Ryazanov
      Pages 127-139
    6. Olivier Radresa, Stephen Zicha, William Brown, Jennifer M. A. Laird
      Pages 221-235
    7. Fabien Vincent, Matthew A. J. Duncton
      Pages 257-270
  4. TRPs and Airways

    1. Front Matter
      Pages 271-271
    2. Alexander Dietrich, Thomas Gudermann
      Pages 273-282
    3. Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, Alexander Dietrich
      Pages 283-300
    4. Zsuzsanna Helyes, Zsófia Hajna
      Pages 301-342
    5. Raffaele Gatti, Pamela Pedretti, Romina Nassini, Marcello Trevisani
      Pages 343-360
    6. Eva Millqvist
      Pages 361-370
  5. TRPs and the Genitourinary (GU) Tract

    1. Front Matter
      Pages 371-371
    2. Ana Charrua, Francisco Cruz
      Pages 373-395
    3. Célia D. Cruz, António Avelino
      Pages 397-409
    4. Roberto Soler, Lysanne Campeau, Claudius Füllhase, Karl-Erik Andersson
      Pages 411-431
  6. Back Matter
    Pages 433-446

About this book

Introduction

Recent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options. Thus, the TRP superfamily of ion channels has attracted a great deal of well-deserved attention.  TRP Channels in Drug Discovery provides a thorough collection of the most up-to-date reviews and protocols on the subject, coming from top experts in the field.  Volume I presents a series of state-of-the-art minireviews on the most interesting TRP channels (from TRPA1 to TRPV4), as well as TRP-related protocols involving airways and the genitourinary tract.  Written for the Methods in Pharmacology and Toxicology™ series, this work includes the kind of detailed description and key implementation advice that ensures successful results in the lab.

 

Comprehensive and cutting-edge, TRP Channels in Drug Discovery serves as an ideal reference for graduate students in academic laboratories as well as for pharmaceutical scientists developing new drugs and clinicians interested in novel drugs in the pipeline.

Keywords

Airways Drug discovery Genitourinary tract Ion channels Pharmaceuticals Preclinical development TRP channelopathies Transient Receptor Potential channels

Editors and affiliations

  • Arpad Szallasi
    • 1
  • Tamás Bíró
    • 2
  1. 1., Transfusion ServicesMonmouth Medical CenterLong BranchUSA
  2. 2.Medical and Health Science Center, Department of PhysiologyUniversity of DebrecenDebrecenHungary

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-62703-077-9
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-076-2
  • Online ISBN 978-1-62703-077-9
  • Series Print ISSN 1557-2153
  • Series Online ISSN 1940-6053
  • Buy this book on publisher's site