Overview
- Editors:
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Karen Joy Shaw
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Department of Infectious Diseases, Johnson and Johnson Pharmaceutical Research and Development, L. L. C., San Diego, USA
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About this book
Leading infectious disease researchers and pharmaceutical scientists comprehensively review the latest genomic technologies and their application to the prevention, diagnosis, and treatment. The authors' cross-disciplinary approach, with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa, reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools. The authors also discuss the application of DNA micoarrays and the impact of genome sequencing comparisons on the discovery and choices of novel drug targets. The result is a better understanding how genomic information can reveal the fundamentals of microbial pathogenesis and how organisms interact with their host environment.
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Table of contents (18 chapters)
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Viruses
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Front Matter
Pages xvii-xvii
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- Steffney Elise Rought, Roman Sasik, Davey Mitchell Smith, Jacques Corbeil
Pages 13-24
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- Yijan Elaine Chang, Laimonis A. Laimins
Pages 25-38
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- Gregory C. Fanning, Janet L. Macpherson, Geoff Symonds
Pages 39-51
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Bacteria
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- Marcel A. Behr, Stephen V. Gordon
Pages 69-81
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- Michael J. Pucci, John F. Barrett, Thomas J. Dougherty
Pages 83-96
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- Brian J. Morrow, Karen Joy Shaw
Pages 97-112
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- Alireza Shamaei-Tousi, Sven Bergström
Pages 133-154
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Fungi
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- Beth DiDomenico, Scott S. Walker
Pages 155-166
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- Marianne D. De Backer, Walter H. M. L. Luyten, Hugo F. Vanden Bossche
Pages 167-196
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- Jennifer K. Lodge, John R. Perfect
Pages 197-214
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- Rosanna Pena-Muralla, Patricia Ayoubi, Marcia Graminha, Nilce M. Martinez-Rossi, Antonio Rossi, Rolf A. Prade
Pages 215-230
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- Theo N. Kirkland, Garry T. Cole
Pages 247-254
Reviews
"As a result of this comprehensive genomic information relying on new technologies and experimental tools, a novel quality in understanding pathogenicity has been reached. This is illustrated in the book in an impressive manner." -Proteomics
Editors and Affiliations
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Department of Infectious Diseases, Johnson and Johnson Pharmaceutical Research and Development, L. L. C., San Diego, USA
Karen Joy Shaw