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The Gene Ontology Handbook

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  • Open Access
  • © 2017

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  • Features chapters on the fundamentals of Gene Ontology, its use in gene annotation, and its application in bioinformatic analyses
  • Emphasizes providing practical guidance and troubleshooting advice
  • Assumes no prior knowledge yet serves as an informative and useful text for experts as well
  • Includes supplementary material:

Part of the book series: Methods in Molecular Biology (MIMB, volume 1446)

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About this book

This book is open access under a CC BY 4.0 license.

This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system.

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Table of contents (21 protocols)

  1. Fundamentals

  2. Making Gene Ontology Annotations

  3. Evaluating Gene Ontology Annotations

  4. Using the Gene Ontology

Editors and Affiliations

  • Department of Genetics Evolution and Environment, University College of London, London, United Kingdom

    Christophe Dessimoz

  • Department of Computer Science, ETH Zurich, Zurich, Switzerland

    Nives Škunca

Bibliographic Information

  • Book Title: The Gene Ontology Handbook

  • Editors: Christophe Dessimoz, Nives Škunca

  • Series Title: Methods in Molecular Biology

  • DOI:

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: The Editor(s) (if applicable) and The Author(s) 2017

  • Hardcover ISBN: 978-1-4939-3741-7Published: 22 November 2016

  • Softcover ISBN: 978-1-4939-8126-7Published: 23 June 2018

  • eBook ISBN: 978-1-4939-3743-1Published: 01 November 2016

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XII, 305

  • Number of Illustrations: 6 b/w illustrations, 50 illustrations in colour

  • Topics: Bioinformatics

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