Overview
- New to this second edition:
- New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs
- Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties
- The work serves as a comprehensive text and reference for students and practitioners of tissue engineering
- Includes supplementary material: sn.pub/extras
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About this book
This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation.
New to this second edition:
New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs
Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties
The work serves as a comprehensive text and reference for students and practitioners of tissue engineering
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Keywords
- Alpha1beta1 integrin
- Alpha2beta1 integrin
- Assay for dermis
- Assay for scar
- Axon elongation
- Bladder Regeneration
- Blocking scar formation
- Collagen fiber orientation
- Collagen scaffold regeneration paradigm
- Collagen-binding integrins
- Contractile cell capsule
- Contractile cells
- Contraction blockade
- Critical axon elongation
- Integrin ligands
- Ligand density of scaffold surface
- Liver Regeneration
- Mechanism of Induced Regeneration
- Mechanism of scar formation
- Molecular biology of scaffold activity
- Myofibroblast orientation
- Myofibroblasts
- Neuroma
- Neuroma blocking
- Peripheral Nerve Regeneration
- Regeneration of Organs
- Regeneration paradigm
- Scaffold regeneration paradigm
- Scar formation
- Skin Regeneration
- Surface chemistry of scaffolds
- Tendon Regeneration
- Tissue Engineering
- Wound Healing Mechanism
- Wound contraction
Table of contents (11 chapters)
Authors and Affiliations
About the author
Bibliographic Information
Book Title: Tissue and Organ Regeneration in Adults
Book Subtitle: Extension of the Paradigm to Several Organs
Authors: Ioannis V. Yannas
DOI: https://doi.org/10.1007/978-1-4939-1865-2
Publisher: Springer New York, NY
eBook Packages: Engineering, Engineering (R0)
Copyright Information: Springer Science+Business Media, LLC 2015
Hardcover ISBN: 978-1-4939-1864-5Published: 21 November 2014
Softcover ISBN: 978-1-4939-5027-0Published: 23 August 2016
eBook ISBN: 978-1-4939-1865-2Published: 21 November 2014
Edition Number: 2
Number of Pages: XXIII, 332
Number of Illustrations: 40 b/w illustrations, 21 illustrations in colour
Topics: Biomedical Engineering and Bioengineering, Biomaterials, Dermatology, Biotechnology