Overview
- Editors:
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Johng S. Rhim
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Laboratory of Cellular and Molecular Biology, National Cancer Institute, Bethesda, USA
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Anatoly Dritschilo
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Department of Radiation Medicine, Georgetown University Medical Center, USA
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Table of contents (38 chapters)
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Viral Transformation and Oncogenes
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- M. Conrad, J. Yankaskas, R. Boucher, R. Schlegel
Pages 163-167
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- L. Braun, M. Dürst, R. Mikumo, A. Blaschke, A. Crowley, K. Rowader
Pages 179-189
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- Elliott Kieff, Fred Wang, Mark Birkenbach, Jeffrey Cohen, Jeffrey Sample, Blake Tomkinson et al.
Pages 191-201
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- Y. Sun, S. Poirier, Y. Cao, G. Hegamyer, N. H. Colburn
Pages 203-212
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- D. Carbone, R. Maneckjee, D. D’Amico, S. Bader, S. Bodner, I. Chiba et al.
Pages 213-221
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- George E. Milo, Hakjoo Lee
Pages 223-232
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Multistep Models
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Front Matter
Pages 233-233
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- N. E. Fusenig, P. Boukamp, D. Breitkreutz, A. Hülsen
Pages 235-250
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- Teresa A. Lehman, Curtis C. Harris
Pages 251-258
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- Martha R. Stampfer, Paul Yaswen, Gordon Parry, Junko Hosoda
Pages 259-267
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- C. A. Reznikoff, C. Kao, E. A. Bookland, A. J. Klingelhutz, C. I. Pratt, S. Q. Wu et al.
Pages 269-280
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- A. C. Williams, A. Manning, S. J. Harper, C. Paraskeva
Pages 281-290
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- A. Haugen, L. Maehle, D. Ryberg, I. L. Hansteen
Pages 291-296
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- Gary D. Stoner, Bret A. Light, Curtis C. Harris
Pages 297-305
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- John F. Lechner, Duane T. Smoot, Andrea M. A. Pfeifer, Katharine H. Cole, Ainsley Weston, John D. Groopman et al.
Pages 307-321
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- Masayoshi Namba, Yoshio Kano, Li-yan Bai, Koichiro Mihara, Masahiro Miyazaki
Pages 323-332
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- D. P. Chopra, A. P. Joiakim, B. Retherford, P. A. Mathieu, J. S. Rhim
Pages 333-341
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- J. L. Rutkowski, J. S. Rhim, K. W. C. Peden, G. I. Tennekoon
Pages 343-346
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- J. Justin McCormick, Veronica M. Maher
Pages 347-357
About this book
The role of carcinogenic agents in the deveolopment of human cancers is now being defined using a variety of human cells as experi mental model systems. A workshop on "neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis" was held at the Georgetown University Medical Center, Washington, DC, on April 25-26, 1991. The aims of the workshop were to present the state-of-the art in the transformation of human cells in culture, as well as to provide insight into the molecular and cellular changes involved in the conver sion of normal cells to a neoplastic state of growth. The following topics were closely related to the theme of the workshops: 1. Derivation of in vitro model systems (epithelial, fibroblastic, and hematopoietic). 2. Factors modulating cellular transformation. 3. Usefulness of defined in vitro model systems for viral, chemical, and radiation carcinogenesis. 4. Multistep nature of human cell carcinogenesis. 5. Role of activated and suppressor oncogenes in neoplastic trans formation. The workshop was organized by J. S. Rhim and A. Dritschilo (cochairmen), G. Jay, J. little, M. McCormick, R Tennant, and R R Weischelbaum. There were 32 speakers, 30 poster presentations, and about 190 participants.
Reviews
...should be a part of any departmental library serving virologists, cell biologists, pathologists, and other scientists interested in malignant cell growth.-Quarterly Review of Biology
Editors and Affiliations
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Laboratory of Cellular and Molecular Biology, National Cancer Institute, Bethesda, USA
Johng S. Rhim
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Department of Radiation Medicine, Georgetown University Medical Center, USA
Anatoly Dritschilo