Advertisement

The Human Brain Circulation

Functional Changes in Disease

  • Rosemary D. Bevan
  • John A. Bevan

Part of the Vascular Biomedicine book series (VB)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. William J. Powers
    Pages 1-22
  3. Jan Erik Hardebo, Norihiro Suzuki
    Pages 37-46
  4. Lars Edvinsson, Sergio Gulbenkian, Inger Jansen, Rolf Uddman
    Pages 47-60
  5. Rosemary D. Bevan, John T. Dodge, Theresa Wellman, Carrie L. Walters, John A. Bevan
    Pages 93-107
  6. Jan Erik Hardebo, Christer Owman
    Pages 109-116
  7. Edith Hamel, François Dauphin, Donald Linville, Vincent Ting, Nadim Zamar
    Pages 117-133
  8. Jan M. Lundberg, Gunvor Ahlborg, Annette Hemsén, Anders Rudehill, Eddie Weitzberg
    Pages 135-144
  9. John M. Quayle, Mark T. Nelson
    Pages 145-156
  10. Kazuyoshi Kurahashi, Hachiro Usui, Hiroaki Shirahase, Hiroshi Jino
    Pages 167-178
  11. John A. Bevan, Rosemary D. Bevan, Alynn Klaasen, Paul Penar, Tina Poseno, Carrie L. Walters
    Pages 179-193
  12. Daniel F. Hanley, David A. Wilson, Richard J. Traystman
    Pages 211-219
  13. Christer Nilsson, Christer Owman
    Pages 221-235
  14. Peter Coyle
    Pages 237-246
  15. Wolfgang Kuschinsky
    Pages 247-258
  16. David W. Busija
    Pages 259-269
  17. James R. Docherty
    Pages 271-280
  18. Mauro Ursino
    Pages 291-318
  19. Else Müller-Schweinitzer
    Pages 319-331
  20. Joseph E. Brayden
    Pages 333-342
  21. Mark A. Helfaer, Jeffrey R. Kirsch, Richard J. Traystman
    Pages 361-371
  22. Eiharu Morikawa, Zhihong Huang, Sami Rosenblatt, Tazuka Yoshida, Michael A. Moskowitz
    Pages 373-387
  23. Ismail Laher, John A. Bevan
    Pages 389-397
  24. Peter Vorkapic
    Pages 399-404
  25. Christopher S. Ogilvy, Alynn Klaasen, Theresa Wellman, Rosemary D. Bevan, John A. Bevan
    Pages 405-412
  26. Pierre Aubineau, Pierrette Mathiau
    Pages 433-444
  27. Back Matter
    Pages 451-456

About this book

Introduction

Much of our knowledge of the cerebral circulation has been derived from studies of species other than human. There is increas­ ing recognition of species differences and concern that studies in animals may be misleading if unquestioningly applied to the human. A dramatic example of this occurred in the early his­ tory of the study of the circulation of the brain. Galen of Pergamo (131-201 AD) described a rete mirabile or "marvelous network" of blood vessels at the base of the human skull that he must have derived from observations of certain animals. This vascular structure was supplied by the carotid arteries which, after penetrating the cranium,"are divided into a large number of very small and thin branches in the region between the cranium and the dura matter. Then . . . intersecting one another they give the impression of having forgotten their way in the brain. But this is not the case. In fact, these numerous arteries rejoin and unite like the roots of a tree trunk. . . . " The authority of Galen's writings dominated scientific thought for about 1500 years. His description of a rete was unques­ tioned by Leonardo de Vinci, who included it in his anatomical sketches. William Harvey's remarkable observations led to his definitive account of the circulation of blood.

Keywords

Alzheimer Nervous System alzheimer's disease brain cerebral ischemia neuropeptides physiology positron emission tomography (PET) tissue

Editors and affiliations

  • Rosemary D. Bevan
    • 1
  • John A. Bevan
    • 1
  1. 1.Totman Laboratory for Human Cerebrovascular Research, Department of PharmacologyUniversity of VermontBurlingtonUSA

Bibliographic information