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Endothelium-Dependent Contraction of Cerebral Arteries

  • Kazuyoshi Kurahashi
  • Hachiro Usui
  • Hiroaki Shirahase
  • Hiroshi Jino
Part of the Vascular Biomedicine book series (VB)

Abstract

Vascular tone is regulated by neuronal and humoral factors to maintain appropriate blood flow. SinceFurchgott and Zawadzki (1980) found the obligatory role of endothelial cells in the vasodilating action of acetylcholine (ACh) (endothelium-depen-dent relaxation, EDR), extensive studies on physiological activities of the endothelium in various vascular preparations have been investigated. Palmer et al. (1987) have identified chemically that the endothelium-derived relaxing factor (EDRF) is nitric oxide(NO). In peripheral arteries, EDRF has been considered to play an important role in regulation of vascular tone.

Keywords

Arachidonic Acid Cerebral Artery Cerebral Vasospasm Cyclooxygenase Inhibitor Arachidonic Acid Metabolite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Kazuyoshi Kurahashi
  • Hachiro Usui
  • Hiroaki Shirahase
  • Hiroshi Jino

There are no affiliations available

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