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Clinical and Experimental Pathology of Lung Cancer

  • Book
  • © 1986

Overview

Editors:
  1. J. G. McVie

    1. Netherlands Cancer Institute, Amsterdam, The Netherlands

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  2. W. Bakker

    1. Department of Pneumology, University Hospital Leiden, The Netherlands

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  3. Sj. Sc. Wagenaar

    1. Department of Pathological Anatomy, Sint Antonius Hospital, Nieuwegein, The Netherlands

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  4. D. Carney

    1. Mater Miserecordia Hospital, Dublin, Ireland

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Part of the book series: Developments in Oncology (DION, volume 39)

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Table of contents (17 chapters)

  1. Front Matter

    Pages I-X
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  2. Histopathologic Typing of Lung Cancer

    • Heine H. Hansen
    Pages 1-6

  3. Squamous Cell Carcinoma and Undifferentiated Large Cell Carcinoma of Lung: Similarities and Differences

    • L. B. Woolner
    Pages 7-18

  4. Adenocarcinoma: Clinical Significance of Subtyping and other Morphologic Factors

    • Yukio Shimosato, Tetsuro Kodama
    Pages 19-33

  5. Pathology of Small Cell Carcinoma of the Lung-Changing Concepts

    • M. J. Matthews
    Pages 35-45

  6. Small Cell Carcinomas Versus (Atypical) Carcinoids

    • B. Corrin
    Pages 47-52

  7. Intra- and Interobserver Problems in the Histopathologic Classification of Malignant Lung Tumors

    • Fred R. Hirsch
    Pages 53-56

  8. Differential Diagnosis of Metastatic Lesions in the Lung

    • D. J. Ruiter
    Pages 57-63

  9. Cytology and Lung Cancer

    • William W. Johnston
    Pages 65-74

  10. Immunocytochemical Assessment of Lung Tumors

    • Fred T. Bosman
    Pages 75-89

  11. Critical Evaluation of New Techniques in the Morphological Diagnosis of Lung Cancer

    • J. D. Elema, L. De Leij, P. Postmus, S. Poppema, T. H. The
    Pages 91-103

  12. Flow Cytometric DNA Analysis in the Study of Small Cell Carcinoma of the Lung

    • L. L. Vindeløv, S. Aa. Engelholm, M. Spang-Thomsen
    Pages 105-112

  13. Clinical Applications of the Biologic Properties of Small Cell Lung Cancer

    • Desmond N. Carney
    Pages 113-121

  14. Peptide Hormones in Lung Cancer

    • C. Gropp
    Pages 123-130

  15. Mechanisms of Oncogenesis

    • A. J. Van Der Eb
    Pages 131-137

  16. Adhesion Mechanisms in Liver Metastasis

    • E. Roos
    Pages 139-148

  17. Application of Monoclonal Antibodies in Imaging and Therapy

    • R. K. Oldham, M. H. West
    Pages 149-163

  18. Current Concepts in the Therapy of Small Cell Lung Cancer

    • L. Austin Doyle, Joseph Aisner
    Pages 165-185

  19. Back Matter

    Pages 187-188
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Keywords

About this book

J. G. MCVIE The impact of therapy on one subset of lung cancer, the "small cell" type has been significant and lasting. The reality of cure for even a fraction of patients with this disease has caused reverberations in the pathology lab where the responsibili. '~y and challenge of diagnosis of this vital sub group lies. No less dramatic has been the discovery that the cell types of lung cancer have recognisable growth characteristics in serum free culture, they are recognisable by patterns of markers and some produce growth factors which autoregulate their eventual fate. Many of the discoveries from the biological studies have impacted on the pathologist in the form of disturbing evidence for a single stem cell origin for all the cell types of lung cancer and in the shape of new facilitation in diagnosis by appli­ cation of immunoperoxidase techniques. Monoclonal antibodies raised against oncogene products, growth factor receptor sites, "bystander" cell membrane proteins can all be applied to cytology specimens and frozen or paraffin fixed tissue sections to aid diagnosis and some can be used in sequential serum assay to monitor therapy and predict prognosis. Adding to these extraordinary tools, the sophistication of electron micro­ scopy and immuno-electrcn microscopy, new techniques for preparation of tissue and novel methods for studying vital cells in "kinesis", you sense the flavour of the future of lung cancer which is captured in this book.

Editors and Affiliations

  • Netherlands Cancer Institute, Amsterdam, The Netherlands

    J. G. McVie

  • Department of Pneumology, University Hospital Leiden, The Netherlands

    W. Bakker

  • Department of Pathological Anatomy, Sint Antonius Hospital, Nieuwegein, The Netherlands

    Sj. Sc. Wagenaar

  • Mater Miserecordia Hospital, Dublin, Ireland

    D. Carney

Bibliographic Information

  • Book Title: Clinical and Experimental Pathology of Lung Cancer

  • Editors: J. G. McVie, W. Bakker, Sj. Sc. Wagenaar, D. Carney

  • Series Title: Developments in Oncology

  • DOI: https://doi.org/10.1007/978-94-009-5036-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishers, Dordrecht 1986

  • Softcover ISBN: 978-94-010-8731-5Published: 05 October 2011

  • eBook ISBN: 978-94-009-5036-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 200

  • Topics: Oncology

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