Abstract
The idea that cancer arises from somatic mutations in cellular genes was recently confirmed when it was discovered that point mutations can activate normal genes so that they will become cancer genes or oncogenes. While it has often been assumed that cancer results from a loss of essential functions by mutation, the recent discoveries have demonstrated that at least some forms of cancer are generated as a result of mutational activation of genes which results in the production of dominant cancer genes.
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© 1986 Martinus Nijhoff Publishers, Dordrecht
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Van Der Eb, A.J. (1986). Mechanisms of Oncogenesis. In: McVie, J.G., Bakker, W., Wagenaar, S.S., Carney, D. (eds) Clinical and Experimental Pathology of Lung Cancer. Developments in Oncology, vol 39. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5036-8_14
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DOI: https://doi.org/10.1007/978-94-009-5036-8_14
Publisher Name: Springer, Dordrecht
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