Sustainable C(sp3)-H Bond Functionalization

  • Jin Xie
  • Chengjian Zhu

Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Also part of the SpringerBriefs in Green Chemistry for Sustainability book sub series (GREENCHEMIST)

Table of contents

About this book


This book highlights major achievements made in the last five years concerning sustainable C(sp3)-H bond functionalization and offers a promising and emerging tool-kit for organic synthesis. The book is divided into three chapters demonstrating key advances in C(sp3)-H bond functionalization. Chapter 1 reviews transition-metal-catalyzed C(sp3)-H bond functionalization using different directing groups, while Chapter 2 addresses the new methods of transition-metal-catalyzed and metal-free C(sp3)-H bond functionalization without directing groups, in addition to briefly highlighting redox-neutral C(sp3)-H bond functionalization. In closing, Chapter 3 examines visible-light photoredox catalysis, an emerging and highly sustainable C(sp3)-H bond functionalization strategy. The book offers an intriguing and useful reference guide for a broad readership working and/or interested in the fields of organic, organometallic, and green chemistry.


sp3 C-H bond activation Sustainable chemistry Palladium catalysis Photoredox catalysis Redox-neutral sp3 C-H functionalization Metal-free C-H functionalization Radical coupling Tandem reactions Oxidative coupling

Authors and affiliations

  • Jin Xie
    • 1
  • Chengjian Zhu
    • 2
  1. 1.School of Chemistry andNanjing UniversityNanjingChina
  2. 2.School of ChemistryNanjing UniversityNanjingChina

Bibliographic information