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Multiple Sclerosis: Bench to Bedside

Global Perspectives on a Silent Killer

  • Book
  • © 2017

Overview

Editors:
  1. Alexzander A. A. Asea

    1. Department of Neuroscience Research, University of Dammam, Damman, Saudi Arabia

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  2. Fabiana Geraci

    1. Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy

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    You can also search for this editor in PubMed   Google Scholar

  3. Punit Kaur

    1. Department of Microbiology, Biochemistry & Immunology, Morehouse School of Medicine, Atlanta, USA

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    You can also search for this editor in PubMed   Google Scholar

  • A collection of the most up-to-date and concise reviews on the critical issues of multiple sclerosis written by experts from around the world
  • A ‘must-read’ and an important reference book for all graduate levels, researchers and clinical practitioners interested in the field of Multiple Sclerosis
  • An up-to-date and authorative account of all aspects of Multiple Sclerosis

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 958)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-viii
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  2. Extracellular Vesicles in Multiple Sclerosis as Possible Biomarkers: Dream or Reality?

    • Maria Magdalena Barreca, Emanuele Aliotta, Fabiana Geraci
    Pages 1-9

  3. Manipulation of Oxygen and Endoplasmic Reticulum Stress Factors as Possible Interventions for Treatment of Multiple Sclerosis: Evidence for and Against

    • Paul Eggleton, Gary R. Smerdon, Janet E. Holley, Nicholas J. Gutowski
    Pages 11-27

  4. Heat Shock Proteins in Multiple Sclerosis

    • Ortan Pinar, Yildirim Akan Ozden, Erkizan Omur, Gedizlioglu Muhtesem
    Pages 29-42

  5. Meaning of Self in Multiple Sclerosis: Implications for Treatment and Rehabilitation

    • Maciej Wilski, Tomasz Tasiemski
    Pages 43-55

  6. Multiple Sclerosis and EIF2B5: A Paradox or a Missing Link

    • Insha Zahoor, Ehtishamul Haq, Ravouf Asimi
    Pages 57-64

  7. Molecular Genetic and Epigenetic Basis of Multiple Sclerosis

    • Zohreh Hojati
    Pages 65-90

  8. Role of Oligodendrocyte Dysfunction in Demyelination, Remyelination and Neurodegeneration in Multiple Sclerosis

    • Adriana Octaviana Dulamea
    Pages 91-127

  9. Clinical Neurophysiology of Multiple Sclerosis

    • Mario Habek, Ivan Adamec, Barbara Barun, Luka CrnoÅ¡ija, Tereza Gabelić, Magdalena Krbot Skorić
    Pages 129-139

  10. Multiple Sclerosis Epidemiology in Europe

    • Daiana Bezzini, Mario A. Battaglia
    Pages 141-159

  11. Timing of Future Remyelination Therapies and Their Potential to Stop Multiple Sclerosis Progression

    • Burcu Zeydan, Moses Rodriguez, Orhun H. Kantarci
    Pages 161-170

  12. Neuroplasticity-Based Technologies and Interventions for Restoring Motor Functions in Multiple Sclerosis

    • Sofia Straudi, Nino Basaglia
    Pages 171-185

  13. Back Matter

    Pages 187-188
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Keywords

About this book

Multiple Sclerosis (MS) is one of the main causes of disability in young adult population. The estimated burden of the disease worldwide is about three million people. The pathogenic mechanism of MS involves both auto immune and degenerative processes. These two mechanisms are thought to determine a combination of events leading to several clinical pattern of disease onset and course. 


Multiple Sclerosis: Bench to Bedside provides the most up-to-date and concise reviews on the critical issues of multiple sclerosis from around the world. This book is written by leaders and experts in the field of multiple sclerosis research and is divided into easy to read sections. Section I focuses on basic science aspects of Multiple Sclerosis, including potential biomarkers, molecular biology, heat shock proteins, oxidative stress, genetic and epigenetics. Section II focuses on clinical and epidemiological aspects of Multiple Sclerosis, including remyelination therapy, neuroplasticity-based technologies and interventions. This is an important reference book and a must-read for Postgraduate Medical Scholars, Basic Science Researchers and Neurologists in Clinical Practice.


Editors and Affiliations

  • Department of Neuroscience Research, University of Dammam, Damman, Saudi Arabia

    Alexzander A. A. Asea

  • Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy

    Fabiana Geraci

  • Department of Microbiology, Biochemistry & Immunology, Morehouse School of Medicine, Atlanta, USA

    Punit Kaur

Bibliographic Information

  • Book Title: Multiple Sclerosis: Bench to Bedside

  • Book Subtitle: Global Perspectives on a Silent Killer

  • Editors: Alexzander A. A. Asea, Fabiana Geraci, Punit Kaur

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-319-47861-6

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-47860-9Published: 25 January 2017

  • Softcover ISBN: 978-3-319-83843-4Published: 15 June 2018

  • eBook ISBN: 978-3-319-47861-6Published: 16 January 2017

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VIII, 188

  • Number of Illustrations: 10 b/w illustrations, 18 illustrations in colour

  • Topics: Neurosciences, Neurology, Immunology, Laboratory Medicine

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