Abstract
Emergence and spread of carbapenemases in Enterobacteriaceae is a cause of concern worldwide, the latest threat being New Delhi metallo-P-β-lactamase (NDM-1). This report is of an orthopedic case with fracture femur managed with internal fxation and bone grafting, who subsequently developed secondary infection with Klebsiella pneumoniae harboring blaNDM-1 gene. Minimum inhibitory concentration (MIC) of imipenem was ≥8 μg/ml by E-test, suggestive of carbapenemase production. Phenotypic and further genotypic detection confrmed the presence of bla gene. The isolate remained susceptible only to tigecycline, colistin, and polymyxin B.
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Gupta, V., Bansal, N., Gupta, R. et al. Klebsiella pneumoniae carrying blaNDM-1 gene in orthopedic practice. IJOO 48, 533–535 (2014). https://doi.org/10.4103/0019-5413.139888
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DOI: https://doi.org/10.4103/0019-5413.139888