Abstract
Minimum or maximum electroshock convulsions administered chronically to rats resulted in increased brain weight, total brain cholinesterase activity, total protein, and total acetylcholinesterase activity depending upon whether or not full convulsions were induced and on the frequency of their induction over a 17–20 week period. Convulsed rats made more errors in an underwater T-maze than rats given subconvulsive shocks or sham controls.
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This research was supported by Contract Nonr-2993(00) between the Office of Naval Research and Stanford Research Institute-
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Pryor, G.T., Otis, L.S. & Uyeno, E. Chronic electroshock: Effects on brain weight, brain chemistry, and behavior. Psychon Sci 4, 85–86 (1966). https://doi.org/10.3758/BF03342190
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DOI: https://doi.org/10.3758/BF03342190