Abstract
Tricyanoaminopropene, a compound suggested as a stimulus to the synthesis of RNA in the brain, was administered to male neonate mice daily from 3 to 16 days of age. When drug-treated animals were compared with controls, given physiological saline during early development, the former showed significant facilitation in the acquisition of an escape response from a water maze.
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1. This study was supported in part by Grants MH 08698-03 and MH 13191-01 from the National Institutes of Health. The author wishes to thank The Upjohn Co. for generously providing the compound (U-9189) used in this study.
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Essman, W.B. Facilitation of maze acquisition by mice with tricyanoaminopropene (TCAP) given during early postnatal development. Psychon Sci 9, 51–52 (1967). https://doi.org/10.3758/BF03330754
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DOI: https://doi.org/10.3758/BF03330754