Abstract
An experiment was conducted to evaluate the effect on kindling behavior of stimulation with 1-Hz current prior to 60-Hz sine-wave stimulation. In the first phase, one group of rats had 30 trials of 1-Hz sine waves, 3 trials/day, 1 h between trials (1-60 group), and then received 30 kindling trials over 10 days. A second group had no stimulation on the initial trials (X-60 group) prior to 30 kindling trials. In a second phase, two other groups were treated in a similar fashion, but after a delay of 30 days. The results were the same in both phases: The 1–60 group showed retarded kindling behavior.
Article PDF
Similar content being viewed by others
References
Cain, D. P., & Corcoran, M. E. Rapid kindling induced by low-frequency stimulation. Neuroscience Abstracts, 1979, 5, 623.
Corcoran, M. E., & Cain, D. P. Kindling of seizures with low-frequency stimulation. Brain Research, 1980, 196, 262–265.
Gaito, J. Introduction to analysis of variance procedures. New York: MSS Information Corporation, 1973.
Gaito, J. The kindling effect as a model of epilepsy. Psychological Bulletin, 1976, 83, 1097–1109. (a)
Gaito, J. An oscillation effect during sequential alternations of unilateral amygdaloid stimulations within the kindling paradigm. Physiological Psychology, 1976, 4, 303–306. (b)
Gaito, J. Suppression of 60-Hz-induced convulsive behavior by 3-Hz brain stimulation. Bulletin of the Psychonomic Society, 1979, 13, 223–226. (a)
Gaito, J. 3-Hz brain stimulation interferes with various aspects of the kindling effect. Bulletin of the Psychonomic Society, 1979, 13, 67–70. (b)
Gaito, J. The effect of variable duration one hertz interference on kindling. Canadian Journal of Neurological Sciences, 1980, 7, 59–64. (a)
Gaito, J. The effect of varying durations of stimulation on the 3-Hz interference effect. Bulletin of the Psychonomic Society, 1980, 15, 211–214. (b)
Gaito, J. Gradient of interference by various frequencies on 60-Hz kindled behavior. Canadian Journal of Neurological Sciences, 1980, 7, 223–226. (c)
Gaito, J. The effect of low frequency and direct current stimulation on the kindling phenomenon in rats. Canadian Journal of Neurological Sciences, 1981, 8, 249–253.
Gaito, J., & Gaito, S. T. Prior treatment with 1-Hz stimulation retards the development of kindling induced by 60-Hz stimulation. Bulletin of the Psychonomic Society, 1980, 15, 351–353.
Gaito, J., & Gaito, S. T. The effect of several inter-trial intervals on the 1-Hz interference effect. Canadian Journal of Neurological Sciences, 1981, 8, 61–65.
Gaito, J., Nobrega, J. N., & Gaito, S. T. Interference effect of 3-Hz brain stimulation on kindling behavior induced by 60-Hz stimulation. Epilepsia, 1980, 21, 73–84.
Goddard, G. V., McIntyre, D. C., & Leech, C. K. A permanent change in brain function resulting from daily electrical stimulation. Experimental Neurology, 1969, 25, 295–330.
Racine, R. J. Modification of seizure activity by electrical stimulation: I. After-discharge threshold. Electroencephalography and Clinical Neurophysiology, 1972, 32, 269–279.
Racine, R. Kindling: The first decade. Neurosurgery, 1978, 3, 234–252.
Wada, J. A., & Sato, M. The generalized convulsive seizure state induced by daily electrical stimulation of the amygdale in split brain cats. Epilepsia, 1975, 16, 417–430.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gaito, J. The effect of prior treatment with 1-Hz stimulation on the kindling phenomenon in rats. Bull. Psychon. Soc. 19, 108–110 (1982). https://doi.org/10.3758/BF03330055
Received:
Published:
Issue Date:
DOI: https://doi.org/10.3758/BF03330055