Abstract
A procedure using tailshock plus body restraint is described for the rapid induction (6 h) of glandular stomach lesions in the rat. In a group of 50 rats, a 92% ulceration rate was achieved.
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McCutcheon, N. B., & Guile, M. N.ESB reduction of shock-restraint induced gastric lesions in rats. Paper presented at the meeting of the Eastern Psychological Association, Hartford, Connecticut, April 1980.
References
Brodie, D. A., &Hanson, H. A study of the factors involved in the production of gastric ulcers by the restraint technique.Gastroenterology, 1960,38, 353–360.
Wald, E. D., MacKinnon, J. R., &Desiderato, O. Production of gastric ulcers in the unrestrained rat.Physiology & Behavior, 1973,10, 825–827
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This research was supported by Giant AM 19673-02 from the National Institute of Arthritis, Metabolism, and Digestive Diseases. The authors thank Scott Nelson for help in collecting data.
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Guile, M.N., McCutcheon, N.B. A tailshock-restraint technique for acute induction of gastric lesions in rats. Behavior Research Methods & Instrumentation 12, 359–360 (1980). https://doi.org/10.3758/BF03201675
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DOI: https://doi.org/10.3758/BF03201675