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Parasitic infections and pregnancy complications

  • Published:
Helminthologia

Summary

Infections of various aetiology during pregnancy present a serious risk factor that can lead to abortion, premature birth, stillbirth, birth of newborn with genetic developmental defects, or seemingly healthy infant that may develop symptoms later in life. A total of 530 sera of patients from gynaecology departments were examined for antibodies against Toxoplasma gondii, Toxocara spp. and Listeria monocytogenes using ELISA (IgG, IgM). In women with habitual abortions we determined up to 42.1 % seroprevalence of IgG antibodies against T. gondii. The prevalence of antibodies was statistically significant (p < 0.0004) when compared to control group (25.1 %). In the patients diagnosed with sterility the prevalence of antibodies (26.3 %) was similar to that of control group. The prevalence of antibodies against Toxocara spp. (5.5 %) and Listeria monocytogenes (2.3 %) in patients with habitual abortions were similar to those of women in the general population.

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References

  • Al-Hamdani, M. M., Mahdi, N. K. (1997): Toxoplasmosis among women with habitual abortion. East. Mediterr. Health J., 3(2): 310–315

    Google Scholar 

  • Andrade, G. M. Q., Vasconcelos-Santos, D. V., Carellos, E. V. M., Romanelli R. M. C., Vitor R. W. A., Carneiro A. C. A. V., Januario J. N. (2010): Congenital toxoplasmosis from a chronically infected woman with reactivation of retinochoroiditis during pregnancy. J. Pediatr. (Rio J.), 86(1): 85–88. DOI: 10.1590/S0021-75572010000100015

    Article  Google Scholar 

  • Bálint, O. (2003): Listeriosis. In: Šašinka, M., Nyulassy, Š., Badalík, L.: Vademecum Medici. Martin, SR: Osveta, pp. 1444–1445 (In Slovak)

    Google Scholar 

  • Benshushan, A., Tsafrir, A., Arbel, R., Rahav, G., Ariel, I., Rojansky, N. (2002): Listeria infection during pregnancy: a 10 year experience. Isr. Med. Assoc. J., 4(10): 776–780

    PubMed  Google Scholar 

  • Bobić, B., Jevremović, I., Marinković, J., Šibalić, D., Djurkovic-djaković, O. (1998): Risk factors for Toxoplasma infection in a reproductive age female population in the area of Belgrade, Yugoslavia. Eur. J. Epidemiol., 14: 605–610

    Article  PubMed  Google Scholar 

  • Citterbart, K. (2001): Gynaecology. 1st Edition, Galen. p. 139 (In Czech)

  • Čatár, G., Červeň, D., Jalili, N. (1998): Toxoplasma gondii. Bratisl. Lek. Listy, 99, 579–583 (In Slovak)

    PubMed  Google Scholar 

  • Decavalas, G., Papaperopoulou, M., Giannoulaki, E., Tzigounis, V., Kondakis, X. G. (1990): Prevalence of Toxoplasma gondii antibodies in gravidas and recently aborted women and study of risk factors. Eur. J. Epidemiol., 6(2): 223–226

    Article  PubMed  CAS  Google Scholar 

  • Ellner, P. D., Neu H. C. (1992): Understanding infectious disease. Mosby Year Book. St. Louis — Y.B.INC, 343 pp.

  • Golledge, C. L., Beaman, M. H. (1990): Toxoplasmosis and pregnancy. Aust. N. Z. J. Obstet. Gynaecol., 30: 32–33. DOI: 10.1111/j.1479-828X.1990.tb03191.x

    Article  PubMed  CAS  Google Scholar 

  • Hejlíček, K., Literák, I., Vostalová, E., Křešnička, J. (1999): Antibodies against Toxoplasma gondii in pregnant women of the České Budějovice District. Epidemiol. Mikrobiol. Imunol., 48: 102–105 (In Czech)

    PubMed  Google Scholar 

  • Hingorani, V., Prakash, O., Chowdhry, P., Kamalam, T. S. (1970): Toxoplasmosis: abortions and stillbirths. Indian J. Med. Res., 58: 967–974

    PubMed  CAS  Google Scholar 

  • Huang, Z. P., Huang, Z. J., Guo, H. (1998): Analysis on Toxoplasma gondii infection in the semina of 140 cases of sterility patients. J. Chin. Birth Cont. (Chin.)., 6: 160–161

    Google Scholar 

  • Hudeček, R., Krajčovičová, R., Ventruba, P. (2009): Pharmacological possibilities of embryoprotective therapy of infertile women. Klin. Farmakol. Farm., 23(2): 76–82 (In Czech)

    Google Scholar 

  • Jirsová, S., Mašata, J., Jech, L., Drbohlav, P., Jaržembovská, M., Pavelková, J., Moosová, M., Řežábek, K., Bencko, V., Zvárová, J. (2009): Levels of chlorinated organic pesticides in follicular liquid of infertile women. Chem. Listy. 103: 589–594 (In Czech)

    Google Scholar 

  • Krajčovičová, R., Hudeček, R., Kalvodová, J. (2007): Differential diagnostics and therapy of repeated pregnancy losses. Prakt. Gyn. 11(4): 164–169 (In Czech)

    Google Scholar 

  • Langer, H. (1963): Repeated congenital infection with T. gondii. Obstet. Gynaecol., 21: 318–329

    CAS  Google Scholar 

  • Luft, B. J., Remington, J. S. (1992): Toxoplasmosis encephalitis in AIDS. Clin. Infect. Dis., 15: 211–222

    PubMed  CAS  Google Scholar 

  • Mahajan, R. C., Gupta, I., Chhapra, M. B., Gupta, A. N., Devi, P. K., Ganguli, N. K. (1976): Toxoplasmosis — its role in abortion. Indian J. Med. Res., 64(6): 797–800

    PubMed  CAS  Google Scholar 

  • Mašta, J., Jedličková, A. (2004): Infections in gynaecology and obstetrics and prinicples of antiinfectious treatment. Praha, CzR: Maxdorf - Jessenius. 371 pp. (In Czech)

    Google Scholar 

  • Ondriska, F., Čatár, G., Vozárová, G. (2003): The significance of complement fixation test in clinical diagnosis of toxoplasmosis. Bratisl. Lek. Listy, 104: 189–196

    PubMed  CAS  Google Scholar 

  • Ondriska, F., Mikulecký, M. (2002): Larval Toxocarosis in humans. Pediatr. pro Praxi, 5: 213–217 (In Slovak)

    Google Scholar 

  • Palička, P., Slabá, H., Zitek, K. (1998): An active approach to influencing the prevalence of Toxoplasmosis in population. Prakt. Gynek., 5(1): 23–27 (In Slovak)

    Google Scholar 

  • Qi, R., Su, X. P., Gao, X. L., Liang, X. L. (2005): Toxoplasma infection in males with sterility in Shenyang, China. Zhonghua Nan Ke Xue, 11: 503–504 (In Chinese with English abstract)

    PubMed  Google Scholar 

  • Rappaport, F., Rabinovitz, M., Toaff, R., Krochik, N. (1960): Genital listeriosis as a cause of repeated abortion. Lancet., 1: 1273

    Article  PubMed  CAS  Google Scholar 

  • Reiterová, K., Kinčeková, J., Halásová, D., Miterpá-Ková, M. (2003): Epidemiology and epizootology of toxocarosis. In: Holková, R., Totková, A., Klobušický, M. (Eds) Proceedings „Current problems of human parasitology“. Bratislava: pp. 14–17 (In Slovak)

  • Remington, J. S., Newell, J. W., Cavanaugh, E. (1964): Spontaneous Abortion and Chronic Toxoplasma — Report of a case, with isolation of the parasite. Obstet. Gynecol., 24(1): 25–31

    PubMed  CAS  Google Scholar 

  • Ross, D. S., Jones, J. L., Lynch, M. F. (2006): Toxoplasmosis, cytomegalovirus, listeriosis, and preconception care. Matern. Child. Health J., 10: 187–191. DOI: 10.10 07/s10995-006-0092-0

    Article  Google Scholar 

  • Řežábek, K. (2008): Infertility Treatment. 4th Edition, Praha, CzR: Grada Publishing, 102 pp. (In Czech)

    Google Scholar 

  • Sahwi, S. Y., Zaki, M. S., Haiba, N. Y., Elsaid, O. K., Anwar, M. Y., Abdrabbo, S. A. (1995): Toxoplasmosis as a cause of repeated abortion. Asia Oceania J. Obstet. Gynaecol., 21(2): 145–148

    Article  CAS  Google Scholar 

  • Sharf, M., Eibschitz, I., Eylan, E. (1973): Latent toxoplasmosis and pregnancy. Obstet. Gynecol., 42(3): 349–354

    PubMed  CAS  Google Scholar 

  • Schlosserová, K., Ondriska, F., Halgoš, J., Beladičová, V., Valentová, D. (2007): Current situation of toxocarosis occurrence in Bratislava. In Holková, R., Tomo, I., Totková, A., Klobušický M. (Eds) Proceedings “Current Problems of Human Parasitology” from http://www.fmed.uniba.sk/fileadmin/user_upload/editors/ustavy/parazitologia/Schlosserova....pdf (In Slovak)

  • Silveira, C. A. M., Ferreiea, R., Muccioll, C., Nussenblatt, R., Belfort-jr, R. (2003): Toxoplasmosis transmitted to a newborn from the mother infected 20 years earlier. Am. J. Ophthalmol., 136: 370–371

    Article  PubMed  Google Scholar 

  • Singh, N. (1998): Status of Toxoplasma antibodies in recurrent fetal loss in U.A.E. women. Indian J. Pediatr., 65: 891–897

    Article  PubMed  CAS  Google Scholar 

  • Southern, P. M. (1972): Habitual abortion and toxoplasmosis. Is there a relationship? Obstet. Gynecol., 39: 45–47

    PubMed  Google Scholar 

  • Stray-pedersen, B., Lorentzen-styr, A. M. (1977): Uterine toxoplasma infections and repeated abortions. Am. J. Obstet. Gynecol., 128(7): 716–721

    PubMed  CAS  Google Scholar 

  • Strhársky, J., Klement, C., Hrubá, F. (2009): Seroprevalence of Toxoplasma gondii antibodies in the Slovak Republic. Folia Microbiol., 54(6): 553–558. DOI: 10.1007/s12223-009-0081-y

    Article  Google Scholar 

  • Studeničová, C., Benčaiová, G., Holková, R. (2006): Seroprevalence of Toxoplasma gondii antibodies in a healthy population from Slovakia. Eur. J. Intern. Med., 17(7): 470–473. DOI: 10.1016/j.ejim.2006.07.007

    Article  PubMed  Google Scholar 

  • Svobodová, V., Literák, I. (1998): Prevalence of IgM and IgG antibodies to Toxoplasma gondii in blood donors in the Czech Republic. Eur. J. Epidemiol., 14: 803–805. DOI: 10.1023/A:1007589422080

    Article  PubMed  Google Scholar 

  • Štork, A. (1981): Medical Textbook, Vol. 1. A-L. Praha, CzR: Avicenum: pp. 972–974 (In Czech)

    Google Scholar 

  • Terpsidis, K. I., Papazahariadou, M. G., Taitzoglou, I. A., Papaioannou, N. G., Georgiadis, M. P., Theodoridis, I. T. (2009): Toxoplasma gondii: Reproductive parameters in experimentally infected male rats. Exp. Parasitol., 121(3): 238–241. DOI: 10.1016/j.exppara.2008.11.006

    Article  PubMed  CAS  Google Scholar 

  • Tomolová, Z., Zmrhal, J., Hradec, D. (2004): Gynaecological Listeriosis as a cause of septic disease of newborns. Prakt. Gyn., 3: 19–21 (In Czech)

    Google Scholar 

  • Turbadkar, D., Mathur, M., Rele, M. (2003): Seroprevalence of torch infection in bad obstetric history. Indian J. Med. Microbiol., 21: 108–110

    PubMed  CAS  Google Scholar 

  • Wilson, C. B., Remington, J. S. (1987): Toxoplasmosis. In: Textbook of Pediatric Infectious Diseases. 2nd Ed.,Vol. II., Philadelphia: W.B. Saunders Comp., pp. 2067–2078

    Google Scholar 

  • Wong, S. Y., Remington, J. S. (1994): Toxoplasmosis in pregnancy. Clin. Infect. Dis., 18: 853–862

    PubMed  CAS  Google Scholar 

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Correspondence to J. Kinčeková.

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Pavlinová, J., Kinčeková, J., Ostró, A. et al. Parasitic infections and pregnancy complications. Helminthologia 48, 8–12 (2011). https://doi.org/10.2478/s11687-011-0002-x

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  • DOI: https://doi.org/10.2478/s11687-011-0002-x

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