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Be aware of the potential for exercise to increase the absorption of medications delivered via a transdermal patch

  • Drug Reactions and Interactions
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Table I
Table II

References

  1. Prausnitz MR, Langer R. Transdermal drug delivery. Nat Biotechnol 2008; 26(11): 1261–8

    Article  PubMed  CAS  Google Scholar 

  2. Lenz TL, Gillespie N. Transdermal patch drug delivery interactions with exercise. Sports Med 2011; 41(3): 177–83

    Article  PubMed  Google Scholar 

  3. Tom W-C. Characteristics of transdermal patches. Pharm Lett 2008 July; 24(7): 240711

    Google Scholar 

  4. Venkatraman S, Gale R. Skin adhesives and skin adhesion: 1. Transdermal drug delivery systems. Biomaterials 1998; 19(13): 1119–36

    Article  PubMed  CAS  Google Scholar 

  5. Barkve TF, Langseth-Manrique K, Bredesen JE, et al. Increased uptake of transdermal glyceryl trinitrate during physical exercise and during high ambient temperature. Am Heart J 1986; 112(3): 537–41

    Article  PubMed  CAS  Google Scholar 

  6. Weber S, de Luture D, Rey E, et al. The effects of moderate sustained exercise on the pharmacokinetics of nitroglycerine. Br J Clin Pharmacol 1987; 23(1): 103–5

    Article  PubMed  CAS  Google Scholar 

  7. Lefebvre RA, Bogaert MG, Teirlynck O, et al. Influence of exercise on nitroglycerin plasma concentrations after transdermal application. Br J Clin Pharmacol 1990; 30(2): 292–6

    Article  PubMed  CAS  Google Scholar 

  8. Gjesdal K, Klemsdal TO, Rykke EO, et al. Transdermal nitrate therapy: bioavailability during exercise increases transiently after the daily change of patch. Br J Clin Pharmacol 1991; 31(5): 560–2

    Article  PubMed  CAS  Google Scholar 

  9. Klemsdal TO, Gjesdal K, Zahlsen K. Physical exercise increases plasma concentrations of nicotine during treatment with a nicotine patch. Br J Clin Pharmacol 1995; 39(6): 677–9

    Article  PubMed  CAS  Google Scholar 

  10. Bur A, Joukhadar C, Klein N, et al. Effects of exercise on transdermal nicotine release in healthy habitual smokers. Int J Clin Pharmacol Ther 2005; 43(5): 239–43

    PubMed  CAS  Google Scholar 

  11. Health Canada. Canadian adverse drug reaction newsletter. Can Med Assoc 1996; 6(1) 154: 61–3

    Google Scholar 

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Be aware of the potential for exercise to increase the absorption of medications delivered via a transdermal patch. Drugs Ther Perspect 28, 19–21 (2012). https://doi.org/10.2165/11208050-000000000-00000

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