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The three ‘A’s of treating chronic prostatitis/chronic pelvic pain syndrome: antibacterials, α-adrenergic receptor antagonists and anti-inflammatory agents

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Table I

References

  1. Murphy AB, Macejko A, Taylor A, et al. Chronic prostatitis: management strategies. Drugs 2009; 69(1): 71–84

    Article  PubMed  CAS  Google Scholar 

  2. Krieger JN, Nyberg Jr L, Nickel JC. NIH consensus definition and classification of prostatitis. JAMA 1999 Jul 21; 282(3): 236–7

    Article  PubMed  CAS  Google Scholar 

  3. McNaughton Collins M, MacDonald R, Wilt TJ. Diagnosis and treatment of chronic abacterial prostatitis: a systematic review. Ann Intern Med 2000 Sep 5; 133(5): 367–81

    Google Scholar 

  4. Nadler RB, Collins MM, Propert KJ, et al. Prostate-specific antigen test in diagnostic evaluation of chronic prostatitis/chronic pelvic pain syndrome. Urology 2006 Feb; 67(2): 337–42

    Article  PubMed  Google Scholar 

  5. Hochreiter WW, Duncan JL, Schaeffer AJ. Evaluation of the bacterial flora of the prostate using a 16S rRNA gene based polymerase chain reaction. J Urol 2000 Jan; 163(1): 127–30

    Article  PubMed  CAS  Google Scholar 

  6. Potts J, Payne RE. Prostatitis: infection, neuromuscular disorder, or pain syndrome? Proper patient classification is key. Cleve Clin J Med 2007 May; 74Suppl. 3: S63–71

    Article  PubMed  Google Scholar 

  7. Nickel JC. Treatment of chronic prostatitis/chronic pelvic pain syndrome. Int J Antimicrob Agents 2008 Feb; 31Suppl. 1: S112–6

    Article  PubMed  CAS  Google Scholar 

  8. Nadler RB. Bladder training biofeedback and pelvic floor myalgia. Urology 2002 Dec; 60(6 Suppl.): 42–3; discussion 4

    Article  PubMed  Google Scholar 

  9. Lee SW, Liong ML, Yuen KH, et al. Adverse impact of sexual dysfunction in chronic prostatitis/chronic pelvic pain syndrome. Urology 2008 Jan; 71(1): 79–84

    Article  PubMed  Google Scholar 

  10. Walz J, Perrotte P, Hutterer G, et al. Impact of chronic prostatitis-like symptoms on the quality of life in a large group of men. BJU Int 2007 Dec; 100(6): 1307–11

    Article  PubMed  Google Scholar 

  11. Nickel JC, Downey J, Johnston B, et al. Predictors of patient response to antibiotic therapy for the chronic prostatitis/chronic pelvic pain syndrome: a prospective multicenter clinical trial. J Urol 2001 May; 165(5): 1539–44

    Article  PubMed  CAS  Google Scholar 

  12. Nickel JC, Downey J, Clark J, et al. Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men: a randomized placebo-controlled multicenter trial. Urology 2003 Oct; 62(4): 614–7

    Article  PubMed  Google Scholar 

  13. Alexander RB, Propert KJ, Schaeffer AJ, et al. Ciprofloxacin or tamsulosin in men with chronic prostatitis/chronic pelvic pain syndrome: a randomized, double-blind trial. Ann Intern Med 2004 Oct 19; 141(8): 581–9

    PubMed  CAS  Google Scholar 

  14. Nickel J, Xiang J. Clinical significance of nontraditional bacterial uropathogens in the management of chronic prostatitis. J Urol 2008 Apr; 179(4): 1391–5

    Article  PubMed  Google Scholar 

  15. Litwin MS, McNaughton-Collins M, Fowler Jr FJ, et al. The National Institutes of Health chronic prostatitis symptom index: development and validation of a new outcome measure. Chronic Prostatitis Collaborative Research Network. J Urol 1999 Aug; 162(2): 369–75

    Article  PubMed  CAS  Google Scholar 

  16. Lee SW, Liong ML, Yuen KH, et al. Chronic prostatitis/chronic pelvic pain syndrome: role of alpha blocker therapy. Urol Int 2007; 78(2): 97–105

    Article  PubMed  CAS  Google Scholar 

  17. Ye ZQ, Lan RZ, Yang WM, et al. Tamsulosin treatment of chronic non-bacterial prostatitis. J Int Med Res 2008 Mar–Apr; 36(2): 244–52

    PubMed  CAS  Google Scholar 

  18. Tugcu V, Tasci AI, Fazlioglu A, et al. A placebo-controlled comparison of the efficiency of triple- and monotherapy in category IIIB chronic pelvic pain syndrome (CPPS). Eur Urol 2007 Apr; 51(4): 1113–7; discussion 8

    Article  PubMed  CAS  Google Scholar 

  19. Nickel JC. Opioids for chronic prostatitis and interstitial cystitis: lessons learned from the 11th World Congress on Pain. Urology 2006 Oct; 68(4): 697–701

    Article  PubMed  Google Scholar 

  20. Nickel JC, Downey J, Pontari MA, et al. A randomized placebo-controlled multicentre study to evaluate the safety and efficacy of finasteride for male chronic pelvic pain syndrome (category IIIA chronic nonbacterial prostatitis). BJU Int 2004 May; 93(7): 991–5

    Article  PubMed  CAS  Google Scholar 

  21. Nickel JC, Forrest JB, Tomera K, et al. Pentosan polysulfate sodium therapy for men with chronic pelvic pain syndrome: a multicenter, randomized, placebo controlled study. J Urol 2005 Apr; 173(4): 1252–5

    Article  PubMed  Google Scholar 

  22. Shoskes DA, Zeitlin SI, Shahed A, et al. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology 1999 Dec; 54(6): 960–3

    Article  PubMed  CAS  Google Scholar 

  23. Rugendorff EW, Weidner W, Ebeling L, et al. Results of treatment with pollen extract (Cernilton N) in chronic prostatitis and prostatodynia. Br J Urol 1993 Apr; 71(4): 433–8

    Article  PubMed  CAS  Google Scholar 

  24. Kaplan SA, Volpe MA, Te AE. A prospective, 1-year trial using saw palmetto versus finasteride in the treatment of category III prostatitis/chronic pelvic pain syndrome. J Urol 2004 Jan; 171(1): 284–8

    Article  PubMed  Google Scholar 

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The three ‘A’s of treating chronic prostatitis/chronic pelvic pain syndrome: antibacterials, α-adrenergic receptor antagonists and anti-inflammatory agents. Drugs Ther. Perspect 25, 13–16 (2009). https://doi.org/10.2165/0042310-200925090-00004

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