Skip to main content
Log in

Japanese encephalitis vaccine (Ixiaro®): a guide to its use as an immunization against Japanese encephalitis virus

  • Drug and Profile Report
  • Published:
Drugs & Therapy Perspectives Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Table I
Fig. 1
Fig. 2
Fig. 3

References

  1. Duggan ST, Plosker GL. Japanese encephalitis vaccine (inactivated, adsorbed) [Ixiaro®]. Drugs 2009; 69(1): 115–22

    Article  PubMed  CAS  Google Scholar 

  2. Centers for Disease Control and Prevention. Travelers’ health: yellow book. Chapter 4. Prevention of specific infectious diseases: Japanese encephalitis [online]. Available from URL: http://www.cdc.gov [Accessed 2009 Jul 21]

  3. Inactivated Japanese encephalitis virus vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). Morb Mortal Wkly Rep 1993; 42 (RR-01): 1–15

    Google Scholar 

  4. World Health Organization. Japanese encephalitis vaccines weekly epidemiological record 2006; 81, 34/35: 331–340 [online]. Available from URL: http://www.who.int [Accessed 2009 Jul 21]

  5. Gould E, Solomon T. Pathogenic flaviviruses. Lancet 2008; 371(9611): 500–9

    Article  PubMed  CAS  Google Scholar 

  6. Solomon T. Control of Japanese encephalitis: within our grasp? N Engl J Med 2006; 355(9): 869–71

    Article  PubMed  CAS  Google Scholar 

  7. Sakaguchi M, Nakashima K, Takahashi H, et al. Anaphylaxis to Japanese encephalitis vaccine. Allergy 2001; 56(8): 804–5

    Article  PubMed  CAS  Google Scholar 

  8. Sugawara K, Nishiyama K, Ishikawa Y, et al. Development of vero cell-derived inactivated Japanese encephalitis vaccine. Biologicals 2002 Dec; 30(4): 303–14

    Article  PubMed  CAS  Google Scholar 

  9. European Medicines Agency. Ixiaro suspension for injection: summary of product characteristics [online]. Available from URL: http://www.emea.europa.eu [Accessed 2009 May 18]

  10. Ixiaro (Japanese encephalitis vaccine, inactivated, adsorbed) suspension for intramuscular injection: US prescribing information. Cambridge (MA): Novartis Vaccines and Diagnostics, Inc., 2009

  11. Tauber E, Kollaritsch H, Korinek M, et al. Safety and immunogenicity of a vero-cell-derived, inactivated Japanese encephalitis vaccine: a non-inferiority, phase III, randomised controlled trial. Lancet 2007 Dec 1; 370(9602): 1847–53

    Article  PubMed  CAS  Google Scholar 

  12. Schuller E, Klade CS, Heinz FX, et al. Effect of pre-existing antitick-borne encephalitis virus immunity on neutralising antibody response to the novel, vero cell-derived, inactivated Japanese encephalitis virus vaccine IC51. Vaccine 2008 Sep 17; 26(48): 6151–6

    Article  PubMed  CAS  Google Scholar 

  13. Lehner C, Eder G, Formica A, et al. Safety and immunogenicity of concomitant vaccination with IC51 and hepatitis A vaccine in healthy subjects: a single-blind randomized controlled phase 3 study [abstract no. 122]. 56th Annual Meeting of the American Society of Tropical Medicine and Hygiene; 2007 Nov 4–8; New Orleans (LA), 36

  14. Schuller E, Jilma B, Voicu V, et al. Long-term immunogenicity of the new vero cell-derived, inactivated Japanese encephalitis virus vaccine IC51: six and 12 month results of a multicenter follow-up phase 3 study. Vaccine 2008 Aug 12; 26(34): 4382–6

    Article  PubMed  CAS  Google Scholar 

  15. Tauber E, Kollaritsch H, von Sonnenburg F, et al. Randomized, double-blind, placebo-controlled phase 3 trial of the safety and tolerability of IC51, an inactivated Japanese encephalitis vaccine. J Infect Dis 2008 Aug 15; 198(4): 493–9

    Article  PubMed  CAS  Google Scholar 

  16. Schuller E, Kishore TSA, Klade C, et al. First clinical trial of a vero cell derived, inactivated Japanese encephalitis (JE) vaccine IC51 in pediatric population [abstract]. 57th Annual Meeting of the American Society of Tropical Medicine and Hygiene; 2008 Dec 7–11; New Orleans (LA)

Download references

Rights and permissions

Reprints and permissions

About this article

Cite this article

Japanese encephalitis vaccine (Ixiaro®): a guide to its use as an immunization against Japanese encephalitis virus. Drugs Ther. Perspect 25, 1–4 (2009). https://doi.org/10.2165/0042310-200925090-00001

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/0042310-200925090-00001

Navigation