Skip to main content
SpringerLink
Log in

Gather and weigh the evidence when judging whether a drug has induced liver injury

  • Drug Reactions and Interaction
  • Published:
Drugs & Therapy Perspectives Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Table I
Table II
Table III

References

  1. Zimmerman H. Hepatotoxicity: the adverse effects of drugs and other chemicals on the liver. Philadelphia (PA): Lippincott Williams & Wilkins, 1999

    Google Scholar 

  2. Abboud G, Kaplowitz N. Drug-induced liver injury. Drug Saf 2007; 30(4): 277–94

    Article  PubMed  CAS  Google Scholar 

  3. Meier Y, Cavallaro M, Roos M, et al. Incidence of drug-induced liver injury in medical inpatients. Eur J Clin Pharmacol 2005; 61(2): 135–43

    Article  PubMed  Google Scholar 

  4. Walgren JL, Mitchell MD, Thompson DC. Role of metabolism in drug-induced idiosyncratic hepatotoxicity. Crit Rev Toxicol 2005; 35(4): 325–61

    Article  PubMed  CAS  Google Scholar 

  5. Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat Rev Drug Discov 2005; 4(6): 489–99

    Article  PubMed  CAS  Google Scholar 

  6. Navarro V. Hepatic adverse event nomenclature document [online]. Available from URL: http://www.fda.gov/cder/livertox/presentations2005/Vic_Navarro.ppt [Accessed 2007 Jul 18]

  7. Björnsson E, Olsson R. Outcome and prognostic markers in severe drug-induced liver disease. Hepatology 2005; 42(2): 481–9

    Article  PubMed  Google Scholar 

  8. Zimmerman H. Drug-induced liver disease. In: Schiff E, editor. Schiff’s diseases of the liver. Baltimore (MD): Lippincott-Raven Publishers, 1999: 973–1064

    Google Scholar 

  9. Zimmerman HJ. Drug-induced liver disease. Clin Liver Dis 2000; 4(1): 73–96, vi

    Article  PubMed  CAS  Google Scholar 

  10. Polson J, Lee WM. AASLD position paper: the management of acute liver failure. Hepatology 2005; 41(5): 1179–97

    Article  PubMed  Google Scholar 

  11. Kaplowitz N. Drug-induced liver injury. Clin Infect Dis 2004; 38Suppl. 2: S44–8

    Article  PubMed  Google Scholar 

  12. Senior J. Regulatory perspectives. In: Kaplowitz N, editor. Drug induced liver diseases. New York: Marcel Dekker, 2003

    Google Scholar 

  13. Nathwani RA, Kaplowitz N. Drug hepatotoxicity. Clin Liver Dis 2006; 10(2): 207–17

    Article  PubMed  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gather and weigh the evidence when judging whether a drug has induced liver injury. Drugs Ther. Perspect 23, 23–26 (2007). https://doi.org/10.2165/00042310-200723110-00008

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00042310-200723110-00008

Search

Navigation