Notes
The use of trade names is for product identification purposes only and does not imply endorsement.
References
Reynolds NA, Lyseng-Williamson KA, Wiseman LR. Inhaled salmeterol/fluticasone propionate: a review of its use in asthma. Drugs 2005; 65(12): 1715–34
Global Initiative for Asthma. GINA report: global strategy for asthma management and prevention (revised 2006) [online]. Available from URL: http://www.ginasthma.com [Accessed 2004 Dec 8]
Glaxo Wellcome UK Limited. Seretide 100, 250, 500 Accuhaler: summary of product characteristics. Uxbridge, UK: Glaxo Wellcome UK Limited, 2006 Nov
Glaxo Wellcome UK Limited. Seretide 50, 125, 250 Evohaler: summary of product characteristics. Uxbridge, UK: Glaxo Wellcome UK Limited, 2006 Nov
GlaxoSmithKline. Advair Diskus 100/50, 250/50, 500/50 prescribing information. Research Triangle Park (NC): GlaxoSmithKline, 2007 Feb
Kirby S, Falcoz C, Daniel MJ, et al. Salmeterol and fluticasone propionate given as a combination: lack of systemic pharmacodynamic and pharmacokinetic interactions. Eur J Clin Pharmacol 2001; 56: 781–91
Bateman ED, Boushey HA, Bousquet J, et al. Can guidelinedefined asthma control be achieved? The Gaining Optimal Asthma controL study. Am J Respir Crit Care Med 2004 Oct; 170(8): 836–44
Strand AM, Luckow A. Initiation of maintenance treatment of persistent asthma: salmeterol/fluticasone propionate combination treatment is more effective than inhaled steroid alone. Danish INitiative for Asthma treatment. Respir Med 2004 Oct; 98(10): 1008–15
Nelson HS, Wolfe JD, Gross G, et al. Efficacy and safety of fluticasone propionate 44 (μg/salmeterol 21 μg administered in a hydrofluoroalkane metered-dose inhaler as an initial asthma maintenance treatment. Ann Allergy Asthma Immunol 2003 Sep; 91(3): 263–9
Murray J, Rosenthal R, Somerville L, et al. Fluticasone propionate and salmeterol administered via Diskus compared with salmeterol or fluticasone propionate alone in patients suboptimally controlled with short-acting β2-agonists. Ann Allergy Asthma Immunol 2004 Oct; 93(4): 351–9
Bergmann K-C, Lindemann L, Braun R, et al. Salmeterol/fluticasone propionate (50/250 μg) combination is superior to double dose fluticasone (500 μg) for the treatment of symptomatic moderate asthma. Swiss Med Wkly 2004 Jan 24; 134(3–4): 50–8
Johansson G, McIvor RA, D’Ambrosio FP, et al. Comparison of salmeterol/fluticasone propionate combination with budesonide in patients with mild-to-moderate asthma. Clin Drug Invest 2001; 21(9): 633–42
Shapiro G, Lumry W, Wolfe J, et al. Combined salmeterol 50 μg and fluticasone propionate 250 μg in the Diskus device for the treatment of asthma. Am J Respir Crit Care Med 2000; 161: 527–34
Busse W, Koenig SM, Oppenheimer J, et al. Steroid-sparing effects of fluticasone propionate 100 μg and salmeterol 50 μg administered twice daily in a single product in patients previously controlled with fluticasone propionate 250 μg administered twice daily. J Allergy Clin Immunol 2003 Jan; 111(1): 57–65
Jenkins C, Woolcock AJ, Saarelainen P, et al. Salmeterol/fluticasone propionate combination therapy 50/250 μg twice daily is more effective than budesonide 800 μg twice daily in treating moderate to severe asthma. Respir Med 2000; 94: 715–23
Kavuru M, Melamed J, Gross G, et al. Salmeterol and fluticasone propionate combined in a new powder inhalation device for the treatment of asthma: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol 2000; 105 (6 Pt 1): 1108–16
Pearlman DS, Peden D, Condemi JJ, et al. Efficacy and safety of fluticasone propionate/salmeterol HFA 134A MDI in patients with mild-to-moderate persistent asthma. J Asthma 2004; 41(8): 797–806
Calhoun WJ, Nelson HS, Nathan RA, et al. Comparison of fluticasone propionate-salmeterol combination therapy and montelukast in patients who are symptomatic on short-acting β2-agonists alone. Am J Respir Crit Care Med 2001 Sep 1; 164: 759–63
Pearlman DS, White MV, Lieberman AK, et al. Fluticasone propionate/salmeterol combination compared with montelukast for the treatment of persistent asthma. Ann Allergy Asthma Immunol 2002 Feb; 88: 227–35
Weiler JM, Nathan RA, Rupp NT, et al. Effect of fluticasone/ salmeterol administered via a single device on exercise-induced bronchospasm in patients with persistent asthma. Ann Allergy Asthma Immunol 2005 Jan; 94(1): 65–72
Aubier M, Pieters WR, Schlösser NJJ, et al. Salmeterol/fluticasone propionate (50/500 μg) in combination in a Diskus inhaler (Seretide) is effective and safe in the treatment of steroid-dependent asthma. Respir Med 1999; 93: 876–84
Bateman ED, Britton M, Carrillo J, et al. Salmeterol/fluticasone combination inhaler: a new, effective and well tolerated treatment for asthma. Clin Drug Invest 1998; 16(3): 193–201
Chapman KR, Ringdal N, Backer V, et al. Salmeterol and fluticasone propionate (50/250 μg) administered via combination Diskus inhaler: as effective as when given via separate Diskus inhalers. Can Respir J 1999 Jan–Feb 28; 6(1): 45–51
Fitzgerald JM, Boulet L-P, Follows RMA. The CONCEPT trial: a 1-year, multicenter, randomized, double-blind, double-dummy comparison of a stable dosing regimen of salmeterol/fluticasone propionate with an adjustable maintenance dosing regimen of formoterol/budesonide in adults with persistent asthma. Clin Ther 2005 Apr; 27(4): 393–406
Dahl R, Chuchalin A, Gor D, et al. EXCEL: a randomised trial comparing salmeterol/fluticasone propionate and formoterol/ budesonide combinations in adults with persistent asthma. Respir Med 2006 Jul; 100(7): 1152–62
Nelson HS, Busse WW, Kerwin E, et al. Fluticasone propionate/ salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast. J Allergy Clin Immunol 2000 Dec; 106(6): 1088–95
Ringdal N, Eliraz A, Pruzinec P, et al. The salmeterol/fluticasone combination is more effective than fluticasone plus oral montelukast in asthma. Respir Med 2003 Mar; 97: 234–41
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Inhaled salmeterol/fluticasone propionate: a guide to its use in asthma. Drugs Ther. Perspect 23, 1–4 (2007). https://doi.org/10.2165/00042310-200723110-00001
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DOI: https://doi.org/10.2165/00042310-200723110-00001