References
Plosker GL, Scott LJ. Retigabine in partial seizures. CNS Drugs 2006; 20(7): 601–8
Perucca E. Retigabine in partial seizures: a viewpoint. CNS Drugs 2006; 20(7): 609
Eadie M. Retigabine in partial seizures: a viewpoint. CNS Drugs 2006; 20(7): 609–10
Walker MC, Sander JW. New anti-epileptic drugs. Expert Opin Investig Drugs 1999 Oct; 8(10): 1497–510
Rundfeldt C, Netzer R. The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits. Neurosci Lett 2000; 282: 73–6
Rundfeldt C, Netzer R. Investigations into the mechanism of action of the new anticonvulsant retigabine: interaction with GABAergic and glutamatergic neurotransmission and with voltage gated ion channels. Arzneimittelforschung 2000 Dec; 50(12): 1063–70
Blackburn-Munro G, Dalby-Brown W, Mirza NR, et al. Retigabine: chemical synthesis to clinical application. CNS Drug Rev 2005 Spring; 11(1): 1–20
Wickenden AD, Yu W, Zou A, et al. Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels. Mol Pharmacol 2000 Sep; 58(3): 591–600
Wickenden AD, Zou A, Wagoner PK, et al. Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells. Br J Pharmacol 2001 Jan; 132(2): 381–4
Porter R, Alves W, Nohria V, et al. Randomized, multicenter, dose-ranging trial of retigabine as adjunctive treatment for partial-onset seizures [abstract no. 0160]. J Neurol Sci 2005; 238 Suppl.: S141
Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures. Costa Mesa (CA): Valeant Pharmaceuticals International, 2006. (Data on file)
Retigabine adjunctive therapy in patients with partial-onset seizures: tolerability of different titration rates in a double-blind trial. Costa Mesa (CA): Valeant Pharmaceuticals International, 2006. (Data on file)
Bialer M, Johannessen SI, Kupferberg HJ, et al. Progress report on new antiepileptic drugs: a summary of the seventh Eilat Conference (EILAT VII). Epilepsy Res 2004; 61: 1–48
Perucca E. The clinical pharmacology and therapeutic use of the new antiepileptic drugs. Fund Clin Pharmacol 2001; 15: 405–17
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Retigabine in partial seizures: profile report. Drugs Ther. Perspect 22, 5–6 (2006). https://doi.org/10.2165/00042310-200622120-00002
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DOI: https://doi.org/10.2165/00042310-200622120-00002