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Consider the interplay of many complex factors in order to avoid or correct overtreatment in epilepsy

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Table I

References

  1. Perucca E, Kwan P. Overtreatment in epilepsy: how it occurs and how it can be avoided. CNS Drugs 2005: 19(11): 897–908

    Article  PubMed  CAS  Google Scholar 

  2. Schmidt D, Elger C, Holmes GL. Pharmacological overtreatment in epilepsy: mechanisms and management. Epilepsy Res 2002; 52: 3–14

    Article  PubMed  Google Scholar 

  3. Perucca E, Dulac O, Shorvon S, et al. Harnessing the clinical potential of antiepileptic drug therapy: dosing optimisation. CNS Drugs 2001; 15: 609–12

    Article  PubMed  CAS  Google Scholar 

  4. Perucca E. General principles of medical treatment. In: Shorvon SD, Perucca E, Fish D, et al., editors, The treatment of epilepsy. Oxford: Blackwell Science, 2003: 139–60

    Google Scholar 

  5. Walker MC, Sander JW. Difficulties in extrapolating from clinical trial data to clinical practice: the case of antiepileptic drugs. Neurology 1997; 49: 333–7

    Article  PubMed  CAS  Google Scholar 

  6. Perucca E, Gram L, Avanzini G, et al. Antiepileptic drugs as a cause of worsening of seizures. Epilepsia 1998; 39: 5–17

    Article  PubMed  CAS  Google Scholar 

  7. Schmidt D, Haenel F. Therapeutic plasma levels of phenytoin, phenobarbital, and carbamazepine: individual variation in relation to seizure frequency and type. Neurology 1984; 34: 1252–5

    Article  PubMed  CAS  Google Scholar 

  8. Lepont-Gilardi H. Indications des dosages plasmatiques des antiepileptiques. Bull Inform Medicament Pharmacovigilance 2006 Jan–Feb; 123: 1

    Google Scholar 

  9. Perucca E. Is there a role for therapeutic drug monitoring of new anticonvulsants? Clin Pharmacokinet 2000; 38: 191–204

    Article  PubMed  CAS  Google Scholar 

  10. Perucca E. Overtreatment in epilepsy: adverse consequences and mechanisms. Epilepsy Res 2002; 52: 25–33

    Article  PubMed  CAS  Google Scholar 

  11. Perucca E. Pharmacoresistance in epilepsy: how should it be defined? CNS Drugs 1998; 10: 171–9

    Article  Google Scholar 

  12. Bourgeois BFD. Reducing overtreatment. Epilepsy Res 2002; 52: 53–60

    Article  PubMed  Google Scholar 

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Consider the interplay of many complex factors in order to avoid or correct overtreatment in epilepsy. Drugs Ther. Perspect 22, 24–26 (2006). https://doi.org/10.2165/00042310-200622090-00008

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