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The risk of toxic effects with aluminium-containing over-the-counter drugs appears slight in patients with normal renal function

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Table I

References

  1. Reinke CM, Breitkreutz J, Leuenberger H. Aluminium in over-the-counter drugs: risks outweigh benefits? Drug Saf 2003; 26(14): 1011–25

    Article  PubMed  CAS  Google Scholar 

  2. Lione A. Aluminum toxicology and the aluminum-containing medications. Pharmacol Ther 1985; 29: 255–85

    Article  PubMed  CAS  Google Scholar 

  3. Peterson CL, Perry DL, Masood H, et al. Characterization of antacid compounds containing both aluminum and magnesium: I. Crystalline powders. Pharm Res 1993; 10(7): 998–1004

    Article  PubMed  CAS  Google Scholar 

  4. Parfitt K, editor. Martindale: the complete drug reference. 32nd ed. London: Pharmaceutical Press, 1999

    Google Scholar 

  5. Berthon G. Aluminium speciation in relation to aluminium bioavailability, metabolism and toxicity. Coord Chem Rev 2002; 228: 319–41

    Article  CAS  Google Scholar 

  6. Ittel TH, Gladziwa U, Muck W, et al. Hyperaluminaemia in critically ill patients: role of antacid therapy and impaired renal function. Eur J Clin Invest 1991; 21: 96–102

    Article  PubMed  CAS  Google Scholar 

  7. Greger JL. Aluminum metabolism. Annu Rev Nutr 1993; 13: 43–63

    Article  PubMed  CAS  Google Scholar 

  8. Zumkley H, Bertram HP, Brandt M, et al. Aluminiumkonzentration in Knochen und Gehirn nach Antazidagabe. Fortschr Med 1987; 105 Suppl. 19: 15–8

    Google Scholar 

  9. Chazan JA, Lew NL, Lowrie EG. Increased serum aluminum. Arch Intern Med 1991; 151: 319–22

    Article  PubMed  CAS  Google Scholar 

  10. Woodson GC. An interesting case of osteomalacia due to antacid use associated with stainable bone aluminum in a patient with normal renal function. Bone 1998; 6: 695–8

    Article  Google Scholar 

  11. McLachlan DRC. Aluminium and the risk for Alzheimer’s disease. Environmetrics 1995; 6: 233–75

    Article  Google Scholar 

  12. Flaten TP. Aluminium as a risk factor in Alzheimer’s disease, with emphasis on drinking water. Brain Res Bull 2001; 55(2): 187–96

    Article  PubMed  CAS  Google Scholar 

  13. Tytgat GN, Heading RC, Mueller-Lissner S, et al. Contemporary understanding and management of reflux and constipation in the general population and pregnancy: a consensus meeting. Aliment Pharmacol Ther 2003; 18(3): 291–301

    Article  PubMed  CAS  Google Scholar 

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The risk of toxic effects with aluminium-containing over-the-counter drugs appears slight in patients with normal renal function. Drugs Ther. Perspect 20, 19–21 (2004). https://doi.org/10.2165/00042310-200420110-00007

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