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Non-cholinergic strategies have a potential role in the management of Alzheimer’s disease

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References

  1. Doraiswamy PM. Non-cholinergic strategies for treating and preventing Alzheimer’s disease. CNS Drugs 2002; 16(12): 811–24

    Article  PubMed  CAS  Google Scholar 

  2. Grutzendler J, Morris JC. Cholinesterase inhibitors for Alzheimer’s disease. Drugs 2001; 61(1): 41–52

    Article  PubMed  CAS  Google Scholar 

  3. Parsons CG, Danysz W, Quack G. Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist: a review of preclinical data. Neuropharmacology 1999 Jun; 38(6): 735–67

    Article  PubMed  CAS  Google Scholar 

  4. Reisberg B, Doody R, Stoffler A, et al. Memantine in moderate-to-severe Alzheimer’s disease. N Engl J Med 2003 Apr 3; 348(14): 1333–41

    Article  PubMed  CAS  Google Scholar 

  5. Reisberg B, Ferris S, Möbius HJ, et al. Long-term treatment with the NMDA antagonist memantine: results of a 24-week, open-label extension study in moderately severe-to-severe Alzheimer’s disease [abstract]. Neurobiol Aging 2002; 23: S555

  6. Rich JB, Rasmussen DX, Folstein MF, et al. Nonsteroidal anti-inflammatory drugs in Alzheimer’s disease. Neurology 1995 Jan; 45(1): 51–5

    Article  PubMed  CAS  Google Scholar 

  7. Wettstein A. Cholinesterase inhibitors and gingko extracts: are they comparable in the treatment of dementia?. Comparison of published placebo-controlled efficacy studies of at least six months’ duration. Phytomedicine 2000 Jan; 6(6): 393–401

    Article  PubMed  CAS  Google Scholar 

  8. Schreiter Gasser U, Gasser T. A comparison of cholinesterase inhibitors and gingko extract in treatment of Alzheimer dementia. Fortschr Med Orig 2001 Nov 29; 119(3–4): 135–8

    PubMed  CAS  Google Scholar 

  9. Panisset M, Gauthier S, Moessler H, et al. Cerebrolysin in Alzheimer’s disease: a randomised, double-blind, placebo-controlled trial with a neurotrophic agent. J Neural Transm 2002 Jul; 109(7–8): 1089–104

    Article  PubMed  CAS  Google Scholar 

  10. Wolozin B, Kellman W, Rousseau P, et al. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Arch Neurol 2000 Oct; 57(10): 1439–43

    Article  PubMed  CAS  Google Scholar 

  11. Shumacker SA, Legault C, Thal L, et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women’s Health Initiative Memory Study: a randomized controlled trial. JAMA 2003 May 28; 289(20): 2651–62

    Article  Google Scholar 

  12. Yakke K. Hormone therapy and the brain: déjà vu all over again? JAMA 2003 May 28; 289(20): 2717–9

    Article  Google Scholar 

  13. Sano M, Ernesto C, Thomas RG, et al. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer’s disease; the Alzheimer’s Disease Cooperative Study. New Engl J Med 1997 Apr 24; 336(17): 1216–22

    Article  PubMed  CAS  Google Scholar 

  14. Janus C. Vaccines for Alzheimer’s disease: how close are we? CNS Drugs 2003; 17(7): 457–74

    Article  PubMed  CAS  Google Scholar 

  15. Regland B, Lehmann W, Abedini I, et al. Treatment of Alzheimer’s disease with clioquinol. Dement Geriatr Cogn Disord 2001 Nov-Dec; 12(6): 408–14

    Article  PubMed  CAS  Google Scholar 

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Non-cholinergic strategies have a potential role in the management of Alzheimer’s disease. Drugs Ther. Perspect 19, 7–10 (2003). https://doi.org/10.2165/00042310-200319100-00003

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