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Cognitive dysfunction is a considerable, yet under-recognised, problem in patients with multiple sclerosis

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References

  1. Lyseng-Williamson KA, Plosker GL. Management of relapsing-remitting multiple sclerosis: defining the role of subcutaneous recombinant interferon-b-1a (Rebif). Dis Manage Health Outcomes 2002; 10(5): 307–25

    Article  CAS  Google Scholar 

  2. Bagert B, Camplair P, Bourdette D. Cognitive dysfunction in multiple sclerosis: natural history, pathophysiology and management. CNS Drugs 2002; 16(7): 445–55

    Article  PubMed  Google Scholar 

  3. Fischer JS, Priore RL, Jacobs LD, et al. Neuropsychological effects of interferon beta-1a in relapsing multiple sclerosis: Multiple Sclerosis Collaborative Research Group. Ann Neurol 2000; 48(6): 885–92

    Article  PubMed  CAS  Google Scholar 

  4. Rudick RA, Fisher E, Lee JC, et al. Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Multiple Sclerosis Collaborative Research Group. Neurology 1999; 53(8): 1698–704

    Article  PubMed  CAS  Google Scholar 

  5. Pliskin NH, Hamer DP, Goldstein DS, et al. Improved delayed visual reproduction test performance in multiple sclerosis patients receiving interferon beta-1b. Neurology 1996; 47(6): 1463–8

    Article  PubMed  CAS  Google Scholar 

  6. Weinstein A, Schwid SI, Schiffer RB, et al. Neuropsychologic status in multiple sclerosis after treatment with glatiramer. Arch Neurol 1999; 56(3): 319–24

    Article  PubMed  CAS  Google Scholar 

  7. Khan O, Zabad R, Caon C, et al. Comparative assessment of immunomodulating therapies for relapsing-remitting multiple sclerosis. CNS Drugs 2002; 16(8): 563–78

    Article  PubMed  CAS  Google Scholar 

  8. Rao SM. Neuropsychology of multiple sclerosis. Curr Opin Neurol 1995; 8(3): 216–20

    Article  PubMed  CAS  Google Scholar 

  9. Rao SM, Leo GL, Ellington L, et al. Cognitive dysfunction in multiple sclerosis: II: impact on employment and social functioning. Neurology 1991; 41(5): 692–6

    Article  PubMed  CAS  Google Scholar 

  10. Amato MP, Ponziani G, Siracusa G, et al. Cognitive dysfunction in early-onset multiple sclerosis: a reappraisal after 10 years. Arch Neurol 2001; 58(10): 1602–6

    Article  PubMed  CAS  Google Scholar 

  11. Greene YM, Tariot PN, Wishard H, et al. A 12-week, open trial of donepezil hydrochloride in patients with multiple sclerosis and associated cognitive impairments. J Clin Psychopharmacol 2000; 20(3): 350–6

    Article  PubMed  CAS  Google Scholar 

  12. Rorie KD, Stump DA, Jeffrey DR. Effects of donepezil on cognitive function in patients with multiple sclerosis [abstract]. Neurology 2001; 56 Suppl. 3: A99

    Google Scholar 

  13. Krupp LB, Alvarez LA, LaRocca NG, et al. Fatigue in multiple sclerosis. Arch Neurol 1988; 45(4): 435–7

    Article  PubMed  CAS  Google Scholar 

  14. Minden SL, Schiffer RB. Affective disorders in multiple sclerosis: review and recommendations for clinical research. Arch Neurol 1990; 47(1): 98–104

    Article  PubMed  CAS  Google Scholar 

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Cognitive dysfunction is a considerable, yet under-recognised, problem in patients with multiple sclerosis. Drugs Ther. Perspect 19, 13–16 (2003). https://doi.org/10.2165/00042310-200319050-00005

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