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Bosentan: profile report

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References

  1. Prakakash A, Perry CM. Bosentan. Am J Cardiovasc Drugs 2002; 2 (5): 335–42

    Article  Google Scholar 

  2. Rubin LJ. Bosentan: a viewpoint. J Cardiovasc Drugs 2002; 2 (5): 343

    Article  Google Scholar 

  3. Wilkins MR, Paul G. Bosentan: a viewpoint. Am J Cardiovasc Drugs 2002: 2 (5) 343

    Article  Google Scholar 

  4. Gaine SP, Rubin LJ. Primary pulmonary hypertension. Lancet 1998 Aug 29; 352: 719–25

    Article  PubMed  CAS  Google Scholar 

  5. Miyauchi T, Masaki T. Pathophysiology of endothelin in the cardiovascular system. Annu Rev Physiol 1999; 61: 391–41

    Article  PubMed  CAS  Google Scholar 

  6. Galie N, Hinderliter AL, Torbicki A, et al. Effects of oral endothelin receptor antagonist bosentan on echocardiographic and Doppler measures in patients with pulmonary artery hypertension [abstract no. 1081–80]. J Am Coll Cardiol 2002 Mar 6; 39 (5 Suppl. A): 224A

    Article  Google Scholar 

  7. Badesch DB, Bodin F, Channick RN, et al. Complete results of the first randomized, placebo-controlled study of bosentan, a dual endothelin receptor antagonist, in pulmonary arterial hypertension. Curr Thera Res 2002 Apr; 63 (4): 227–46

    Article  CAS  Google Scholar 

  8. Channick RN, Simonneau G, Sitbon O, et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 2001 Oct 6; 358 (9288): 1119–23

    Article  PubMed  CAS  Google Scholar 

  9. Rubin LJ, Badesch DB, Barst RJ, et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 2002 Mar 21; 346 (12): 896–903

    Article  PubMed  CAS  Google Scholar 

  10. Pereira BN, Salvi S, Dietrich CG, et al. Bosentan for pulmonary hypertension. N Engl J Med 2002; 347: 292–4

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. University of California, San Diego School of Medicine, La Jolla, California, USA

    Lewis J. Rubin

  2. Section on Clinical Pharmacology, Imperial College, Hammersmith Hospital, London, UK

    Martin R. Wilkins & Gideon Paul

Authors
  1. Lewis J. Rubin
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  2. Martin R. Wilkins
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  3. Gideon Paul
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Rubin, L.J., Wilkins, M.R. & Paul, G. Bosentan: profile report. Drugs Ther. Perspect 19, 5–6 (2003). https://doi.org/10.2165/00042310-200319010-00002

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  • DOI: https://doi.org/10.2165/00042310-200319010-00002

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