References
Rofecoxib: a review of its use in the management of osteoarthritis, acute pain and rheumatoid arthritis. Drugs. 2001 May; 61 (6); 833-65
Jackson LM, Hawkey CJ. COX-2 selective nonsteroidal anti-inflammatory drugs: do they really offer any advantages? Drugs 2000 Jun; 59 (6): 1207–16
Singh G, Triadafilopoulos G. Epidemiology of NSAID induced gastrointestinal complications. J Rheum 1999; 26 Suppl. 56: 18–24
Golden BD, Abramson SB. Selective cyclo-oxygenase-2 inhibitors. Rheum Dis Clin North Am 1999; 25 (2); 359–78
Cannon GW. Cyclo-oxygenase-2 selective inhibitors. Drugs Today 1999; 35 (7); 487–96
Vane JR, Botting RM. Mechanism of action of anti-inflammatory drugs. Int J Tiss React 1998; 20 (1); 3–15
Geba GP, Weaver AL, Schnitzer TJ, et al. A clinical trial comparing rofecoxib to celecoxib and acetaminophen in the treatment of osteoarthritis (OA): early results [abstract]. Ann Rheum Dis 2000; 59 Suppl. 1: 133–4
Daniels B, Krupa D, Ehrich E, et al. Clinical response of OA patients who use acetaminophen when randomized to rofecoxib or ibuprofen [abstract]. Arthritis Rheum 1999; 42 (Suppl.): S143
Day R, Morrison B, Luza A, et al. A randomized trial of the efficacy and tolerability of the COX-2 inhibitor rofecoxib vs ibuprofen in patients with osteoarthritis. Arch Intern Med 2000; 160: 1781–7
Sagg K, van der Heijde D, Fisher C, et al. Rofecoxib, a new cyclooxygenase 2 inhibitor, shows sustained efficacy, comparable with other nonsteroidal anti-inflammatory drugs. Arch Fam Med 2000; 9 (10); 1124–34
van Kuijk C, Cheng X, Hottya G. the effects of rofecoxib and diclofenac on knee osteoarthritis (OA) articular cartilage: the results from one-year prospective clinical trials [abstract no. OP-082]. Ann Rheum Dis 2000; 59 Suppl. 1: 55
Bombardier C, Laine L, Reicin A, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N Eng J Med 2000 Nov 23; 343: 1520–8
Ehrich EW, Dallob A, DeLepeleire I, et al. Characterization of rofecoxib as a cyclo-oxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model. Clin Pharm Ther 1999; 65: 336–47
Malmstron K, Daniels S, Kotey P, et al. Comparison of rofecoxib and celecoxib, two cyclooxgenase-2 inhibitors, in postoperative dental pain: a randomized, placebo- and active-comparator controlled clinical trial. Clin Ther 1999; 21: 1653–63
Morrison BW, Daniels SE, Kotey P, et al. Rofecoxib, a specific cyclooxygenase-2 inhibitor, in primary dysmenorrhoea: a randomized controlled trial. Obstet Gynecol 1999; 94: 504–8
Reuben SS, Connely NR. Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery. Anesth Analg 2000; 91: 1221–5
Reicin A, Brown J, Jove M, et al. Efficacy of single-dose and multidose rofecoxib in the treatment of post-orthopedic surgery pain. Am J Ortho 2001; 30 (1); 40–8
Huang J, Taguchi A, Hsu H, et al. Preoperative oral rofecoxib does not decrease postoperative pain after radical prostatectomy. A prospective randomized, double-blind, placebo-controlled trial [abstract 941]. 2000 Annual Meeting of the American Society of Anesthesiologists, St Louis (MO)
Langman MJ, Jensen DM, Watson DJ, et al. Adverse upper gastrointestinal effects of rofecoxib compared with NSAIDs. JAMA 1999 Nov 24; 282: 1929–33
Watson DJ, Harper SE, Zhao P-L, et al. Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis. Arch Intern Med 2000 Oct 23; 160: 2998–3003
Bombardier C, Laine L, Reicin A. Fewer gastrointestinal protective agents, procedures and hospitalizations with rofecoxib vs. naproxen in the VIGOR (VIOXX GI outcomes research) study [abstract no. 49]. Arthritis Rheum 2000; 43 Suppl: 225
Cannon GW, Caldwell JR, Holt P, et al. Rofecoxib. a specific inhibitor of cyclooxygenase 2, with clinical efficacy comparable with that of diclofenac sodium: results of a one-year, randomized, clinical trial in patients with osteoarthritis of the knee and hip. Arthritis Rheum 2000; 43: 978–987
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Rofecoxib: a selective and effective COX-2 inhibitor. Drugs Ther. Perspect 18, 1–3 (2002). https://doi.org/10.2165/00042310-200218020-00001
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DOI: https://doi.org/10.2165/00042310-200218020-00001