References
Mabro M, Faivre S, Raymond E. A risk-benefit assessment of amifostine in cytoprotection. Drug Saf 1999; 21(5): 367–87
Culy CR, Spencer CM. Amifostine. An update of its clinical status as a cytoprotectant in patients with cancer receiving chemotherapy or radiotherapy and its potential therapeutic application in myelodysplastic syndrome. Drugs 2001; 61(5): 641–84
Kemp G, Rose P, Lurain J, et al. Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized controlled trial in patients with advanced ovarian cancer. J Clin Oncol 1996; 14: 2101–12
Budd GT, Ganapathi R, Adelstein DJ, et al. Randomized trial of carboplatin plus amifostine versus carboplatin alone in patients with advanced solid tumors. Cancer 1997; 80: 1134–40
Anderson H, Mercer V, Thatcher N. A phase III randomised trial of carboplatin and amifostine versus carboplatin and G-CSF in patients with inoperable non-small cell lung cancer (NSCLC) [abstract]. 34th Proc Am Soc Clin Oncol 1998; 17: Los Angeles (CA), 465a
Gold MA, Walker JL, Berek JS, et al. Amifostine pretreatment for protection against topotecan-induced hematologic toxicity: results of a multicenter phase II trial in patients with advanced gynecologic malignancies [abstract]. Gynecol Oncol 2000; 76: 279
Gelmon K, Eisenhauer E, Bryce C, et al. Randomized phase II study of high-dose paclitaxel with or without amifostine in patients with metastatic breast cancer. J Clin Oncol 1999; 17: 3038–47
Hartmann J, von Vangerow A, Fels LM, et al. A randomised trial of amifostine in patients with high-dose VIC chemotherapy plus autologous blood stem cell transplantation. Br J Cancer 2001; 84(3): 313–20
Patriarca F. Amifostine pretreatment for protection against melphalan + busulfan-induced toxicity in high-dose therapy for multiple myeloma patients [abstract no. 5034]. Blood 1999; 94 Suppl. I (Pt 2): 404b
Brizel DM, Wasserman TH, Henke M, et al. Phase III randomized trial of amifostine as a radioprotector in head and neck cancer. J Clin Oncol 2000; 18(19): 3339–45
Antonadou D, Coliarakis N, Synodinou M, et al. Randomized phase III trial of radiation ± amifostine in patients with advanced stage lung cancer [abstract no. 18] Int J Radiat Oncol Biol Phys 1999; 45 Suppl. 3: 154
Bennett CL, Golub R, Calhoun E, et al. Cost-utility assessment of amifostine in first-line therapy for ovarian cancer [abstract]. Int J Gynecol Cancer 1998; 8: 64–72
Alva Pharmaceuticals. Ethyol (amifostine) for injection product information. Available from URL: http://www.ethyol.com/pros/pi.htm [Accessed 2001 Aug 3]
British National Formulary. No. 41 London: The Pharmaceutical Press, 2001 Mar
Rights and permissions
About this article
Cite this article
Amifostine protects a broad range of normal tissues from chemotherapy-and radiotherapy-associated toxicity. Drugs Ther. Perspect 17, 1–5 (2001). https://doi.org/10.2165/00042310-200117210-00001
Published:
Issue Date:
DOI: https://doi.org/10.2165/00042310-200117210-00001