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Topiramate: increasing the choice for patients with refractory partial epilepsy

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References

  1. Pledger GW, Schmidt D. Evaluation of antiepileptic drug efficacy: a review of clinical trial design. Drugs 1994; 48(8): 498–509

    Article  PubMed  CAS  Google Scholar 

  2. Shorvon SD. The epidemiology and treatment of chronic and refractory epilepsy. Epilepsia 1996; 37 Suppl. 2: S1–30

    Article  PubMed  Google Scholar 

  3. Langtry HD, Gillis JC, Davis R. Topiramate: a review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of epilepsy. Drugs 1997 Nov; 54(5): 752–73

    Article  PubMed  CAS  Google Scholar 

  4. British National Formulary. No. 37. London: The Pharmaceutical Press, 1999 Mar

  5. PDR Generics 5th ed. Montvale NJ: Medical Economics, 1999

  6. Reife R, Pledger G, Lim P, et al. Topiramate: pooled analysis of six placebo-controlled trials [abstract]. Epilepsia 1996; 37 Suppl. 4: 74

    Google Scholar 

  7. Rosenfeld WE, Sachdeo RC, Faught RE, et al. Long-term experience with topiramate as adjunctive therapy and as monotherapy in patients with partial onset seizures: retrospective survey of open-label treatment. Epilepsia 1997; 38 Suppl. 1: S34–6

    Article  PubMed  CAS  Google Scholar 

  8. Marson AG, Kadir ZA, Chadwick DW. New antiepileptic drugs: a systematic review of their efficacy and tolerability. BMJ 1996 Nov 9; 313: 1169–74

    Article  PubMed  CAS  Google Scholar 

  9. Elferink AJA, Van Zweiten-Boot BJ. Analysis based on number needed to treat shows differences between drugs studied [letter]. BMJ 1997 Feb 23; 314: 603

    PubMed  CAS  Google Scholar 

  10. Topiramate as adjunctive therapy in partial-onset seizures: the spectrum from adults to children. AED News 1997 Jun 29: 1

    Google Scholar 

  11. Elterman R, Glauser T, Ritter FJ, et al. Efficacy and safety of topiramate in partial seizures in children [abstract]. Neurology 1997 Jun; 48: 1729

    Google Scholar 

  12. Elwood W. New horizons for topiramate in epilepsy. Inpharma 1998 Feb 14; 1124: 13–4

    Google Scholar 

  13. Glauser TA, Sachdeo RC, Ritter FJ, et al. Topiramate in Lennox Gastaut-syndrome: a double-blind trial [abstract]. Neurology 1997 Jun; 48: 1729

    Google Scholar 

  14. Expanding the options of Lennox-Gastaut syndrome: efficacy and tolerability of topiramate. AED News 1997 Jun 29: 3

    Google Scholar 

  15. Glauser TA. Preliminary observations on topiramate in pediatric epilepsies. Epilepsia 1997; 38 Suppl. 1: S37–41

    Article  PubMed  CAS  Google Scholar 

  16. Shorvon SD. Safety of topiramate: adverse events and relationships to dosing. Epilepsia 1996; 37 Suppl. 2: 18–22

    Article  Google Scholar 

  17. Economic impact of refractory epilepsy in the US. Pharmacoecon Outcomes News 1996 Jun 1; 64: 6

    Google Scholar 

  18. van Hout B, Gagnon D, Martens L, et al. Cost-effectiveness of topiramate as add-on therapy in stable refractory patients with partial-onset epilepsy [abstract]. Epilepsia 1997; 38 Suppl. 3: 42

    Google Scholar 

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Topiramate: increasing the choice for patients with refractory partial epilepsy. Drugs Ther. Perspect 14, 1–5 (1999). https://doi.org/10.2165/00042310-199914030-00001

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