References
Selkoe DJ. Aging brain, aging mind. Sei Am 1992; 267: 135–42
Bryson HM, Benfield P. Donepezil. Drugs Aging 1997 Mar; 10(3): 234–9
Wagstaff AJ, McTavish D. Tacrine: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in Alzheimer’s disease. Drugs Aging 1994 Jun; 4: 510–40
Gillis JC, Benfield P, McTavish D. Idebenone: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in age-related cognitive disorders. Drugs Aging 1994 Aug; 5: 133–52
Rho JP, Lipson LG. Focus on donepezil. Formulary 1997 Jul; 32(7): 677–84
Watkins PB, Zimmerman HJ, Knapp MJ. Hepatotoxic effects of tacrine administration in patients with Alzheimer’s disease. JAMA 1994 Apr 6; 271: 992–8
Aniracetam: preliminary evidence of efficacy warrants further comparative studies. Drug Ther Perspect 1994 Oct 3; 4 (7): 4–7
Tacrine offers modest benefits in some patients with Alzheimer’s disease. Drug Ther Perspect 1994 Dec 12; 4 (12): 1–4
Rogers SL, Walters EJ, Friedhoff LT. The pharmacokinetics (PK) and pharmacodynamics(PD) of E2020, ((R,S,)-1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)-methylpiperidine hydrochloride), a novel inhibitor of acetylcholinesterase (AChE): implications for use in the treatment of Alzheimer’s disease [abstract]. Neurobiol Aging 1992; 13(1): 496
Rogers SL, Friedhoff LT, Donepezil Study Group. The efficacy and safety of donepezil in patients with Alzheimer’s disease: results of a US multicentre, randomized, double-blind, placebo-controlled trial. Dementia 1996; 7: 293–303
Mihara M, Ohnishi A, Tomono Y, et al. Pharmacokinetics of E2020, a new compound for Alzheimer’s disease, in healthy male volunteers. Int J Clin Pharmacol Ther Toxicol 1993 May; 31: 223–9
Rogers SL, Doody R, Mohs R. E2020 produces both clinical global and cognitive test improvement in patients with mild to moderately severe Alzheimer’s disease: results of a 30-week phase III trial [abstract]. Neurology 1996 Feb; 46 Suppl.: A217
Rogers SL, Perdomo C, Friedhoff LT. Clinical benefits are maintained during long-term treatment of Alzheimer’s disease with the acetylcholinesterase inhibitor, E2020 [abstract no. P-8-21]. Eur Neuropsychopharmacol 1995; 5(3): 386–7
Stern RG, Mohs RC, Davidson M, et al. A longitudinal study of Alzheimer’s disease: measurement, rate, and predictors of cognitive deterioration. Am J Psychiatry 1994 Mar; 151: 390–6
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Donepezil: a step forward compared with tacrine for Alzheimer’s disease?. Drugs Ther. Perspect 11, 6–8 (1998). https://doi.org/10.2165/00042310-199811030-00002
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DOI: https://doi.org/10.2165/00042310-199811030-00002