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Ibutilide terminates atrial fibrillation/flutter —but watch for proarrhythmia

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References

  1. Foster RH, Wilde MI, Markham A. Ibutilide: a review of its pharmacological properties and clinical potential in the acute management of atrial flutter and fibrillation. Drugs 1997 Aug; 54(2): 312–30

    Article  PubMed  CAS  Google Scholar 

  2. Ellenbogen KA, Stambler BS, Wood MA, et al. Efficacy of intravenous ibutilide for rapid termination of atrial fibrillation and atrial flutter: a dose-response study. J Am Coll Cardiol 1996 Jul; 28: 130–6

    Article  PubMed  CAS  Google Scholar 

  3. Stambler BS, Wood MA, Ellenbogen KA, et al. Efficacy and safety of repeated intravenous doses of ibutilide for rapid conversion of atrial flutter or fibrillation. Circulation 1996 Oct 1; 94: 1613–21

    Article  PubMed  CAS  Google Scholar 

  4. News from the 46th Annual Scientific Sessions of the American College of Cardiology. Anaheim, US, March 1997. Ibutilide for arrhythmia termination after cardiac surgery. Inpharma 1997 Apr 12; (1082): 12

  5. Stambler BS, Wood MA, Ellenbogen KA. Comparative efficacy of intravenous ibutilide versus procainamide for enhancing termination of atrial flutter by atrial overdrive pacing. Am J Cardiol 1996 May 1; 77: 960–6

    Article  PubMed  CAS  Google Scholar 

  6. Stambler BS, Wood MA, Belz MK, et al. Electrophysiologic determinants of pharmacologic conversion of human atrial fibrillation and flutter: enhanced efficacy of ibutilide a new class III antiarrhythmic drug [abstract]. Circulation 1993 Oct; 88 Suppl. (Pt 2): 445

    Google Scholar 

  7. Volgman AS, Stambler BS, Kappagoda C, et al. Comparison of intravenous ibutilide versus procainamide for the rapid termination of atrial fibrillation or flutter [abstract]. Pace 1996 Apr; 19(Pt II): 608

    Google Scholar 

  8. Johns TE, Hancock WW, Lopez LM. Does intravenous ibutilide cause ventricular tachycardia? [abstract no. 5]. Pharmacotherapy 1997; 17(5): 1080–1

    Google Scholar 

  9. Pharmacia & Upjohn Inc. Corvert™ prescribing information. Kalamazoo, USA, 1996

  10. Zarkin GA, Bala MV, Calingaert B, et al. Cost-effectiveness of a stepped treatment regimen of ibutilide followed by electrical cardioversion in the treatment of atrial fibrillation and flutter [abstract CD2]. Am J Manage Care 1997 Mar; 3 (3 Suppl.): S43

    Google Scholar 

  11. Singletary TJ, Malone DC, Wortman GC. Cost-effectiveness analysis of pharmacologic cardioversion for ambulatory atrial arrhythmias [abstract no. 162]. Pharmacotherapy 1997; 17(5): 1106

    Google Scholar 

  12. Zack PM, Grimm MF, Choo EB, et al. Intravenous ibutilide for conversion of atrial fibrillation and atrial flutter: reduction in duration and cost of hospitalization [abstract]. J Invest Med 1997 Mar; 45(3): 211A

    Google Scholar 

  13. Geraets DR, Kienzle MG. Atrial fibrillation and atrial flutter. Clin Pharm 1993 Oct; 12: 721–35

    PubMed  CAS  Google Scholar 

  14. British National Formulary No. 34. London: The Pharmaceutical Press, 1997 Sep

  15. Gill J, Heel RC, Fitton A. Amiodarone: an overview of its pharmacological properties,and review of its therapeutic use in cardiac arrhythmias. Drugs 1992; 43(1): 69–110

    Article  PubMed  CAS  Google Scholar 

  16. Fitton A, Sorkin EM. Sotalol: an updated review of its pharmacological properties and therapeutic use in cardiac arrhythmias. Drugs 1993 Oct; 46: 678–719

    Article  PubMed  CAS  Google Scholar 

  17. 1997 Mosby’s complete drug reference. Physicians GenRx®. 7th ed. St Louis, Missouri: Mosby-Year Book, Inc., 1997

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Ibutilide terminates atrial fibrillation/flutter —but watch for proarrhythmia. Drugs Ther. Perspect 11, 1–5 (1998). https://doi.org/10.2165/00042310-199811030-00001

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