References
Marder VJ. Thrombolytic therapy: overview of results in major vascular occlusions. Thromb Haemost 1995 Jul; 74(1): 101–5
Gillis JC, Wagstaff AJ, Goa KL. Alteplase: a reappraisal of its pharmacological properties and therapeutic use in acute myocardial infarction. Drugs 1995 Jul; 50(1): 102–36
Wagstaff AJ, Gillis JC, Goa KL. Alteplase: a reappraisal of its pharmacology and therapeutic use in vascular disorders other than acute myocardial infarction. Drugs 1995 Aug; 50(2): 289–316
Francis CW, Marder VJ. Fibrinolytic therapy for venous thrombosis. Prog Cardiovasc Dis 1991 Nov/Dec; 34(3): 193–204
Genentech Inc. Alteplase recombinant prescribing information. South San Francisco, California, USA, 1995
Goldhaber SZ, Haire WED, Feldstein ML, et al. Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion. Lancet 1993 Feb 27; 31: 507–11
Goldhaber SZ, Kessler CM, Heit J, et al. Randomised controlled trial of recombinant tissue plasminogen activator versus urokinase in the treatment of acute pulmonary embolism. Lancet 1988 Aug 6; 2: 293–8
Goldhaber SZ, Kessler CM, Heit J, et al. Recombinant tissue-type plasminogen activator versus a novel dosing regimen of urokinase in acute pulmonary embolism: a randomized controlled multicenter trial. J Am Coll Cardiol 1992 Jul; 20: 24–30
Goldhaber SZ, Agnelli G, Levine MN, et al. Reduced dose bolus alteplase vs conventional alteplase infusion for pulmonary embolism thrombolysis. Chest 1994; 106: 718–24
Sors H, Pacouret G, Azarian R, et al. Hemodynamic effects of bolus vs 2-h infusion of alteplase in acute massive pulmonary embolism. Chest 1994; 106: 712–7
Verhaege R, Besse P, Bounameaux H, et al. Multicenter pilot study of the efficacy and safety of systemic rt-PA administration in the treatment of deep vein thrombosis of the lower extremities and/or pelvis. Thromb Res 1989 Jul 1; 55: 5–11
Goldhaber SZ, Meyerovitz MF, Green D, et al. Randomized controlled trial of tissue plasminogen activator in proximal deep venous thrombosis. Am J Med 1990 Mar; 88: 235–40
Turpie AGG, Levine MN, Hirsh J, et al. Tissue plasminogen activator (rt-PA) vs heparin in deep vein thrombosis. Results of a randomized trial. Chest 1990 Apr; 97 Suppl.: 172–5
The STILE Investigators. Results of a prospective randomized trial evaluating surgery versus thrombolysis for ischaemia of the lower extremity. Ann Surg 1994; 220(3): 251–68
The TIMI IIIA Investigators. Early effects of tissue type plasminogen activator added to conventional therapy on the culprit coronary lesion in patients presenting with ischaemic cardiac pain at rest; results of the Thrombolysis in Myocardial Ischaemia (TIMI IIIA) trial. Circulation 1993; 87: 38–52
The TIMI IIIB Investigators. Effects of tissue plasminogen activator and a comparison of early invasive and conservative strategies in unstable angina and non-Q-wave myocardial infarction; results of the Thrombolysis in Myocardial Ischaemia (TIMI IIIB) trial. Circulation 1994; 89: 1545–56
Verstraete M, Bachmann F, Davidson JF, et al. The present status of thrombolytic treatment in noncardiac disorders. J Intern Med 1994; 236: 447–54
Barnes J. ECASS researchers cannot recommend alteplase for stroke. Inpharma 1995 Feb; 18(974): 3–4
Adams HP, Brott TG, Crowell RM, et al. Guidelines for the management of patients with acute ischaemic stroke. Stroke 1994 Sep; 25(9): 1901–14
British National Formulary No. 29. London: The Pharmaceutical Press, 1995; 105–6
Buar FW, Verheugt FW, Col J, et al. Thrombolysis in patients with unstable angina improves the angiographic but not the clinical outcome. Results of UNASEM, a multicenter, randomized, placebo-controlled, clinical trial with anistreplase. Circulation 1992 Jul; 86: 131–7
Anon. Some stroke patients may benefit from streptokinase. Inpharma 1995 Mar 11; (977): 5
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Alteplase is useful in some indications other than myocardial infarction. Drugs Ther. Perspect 6, 1–4 (1995). https://doi.org/10.2165/00042310-199506110-00001
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DOI: https://doi.org/10.2165/00042310-199506110-00001