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Fixed-dose antihypertensive drug combinations may be useful if dual therapy is clinically indicated

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References

  1. Sica DA. Fixed-dose combination antihypertensive drugs. Do they have a role in rational therapy? Drugs 1994; 48: 16–24

    Article  PubMed  CAS  Google Scholar 

  2. Guidelines sub-committee. 1993 guidelines for the management of mild hypertension: memorandum from a World Health Organization/International Society of Hypertension meeting. J Hypertens 1993; 11: 905–18

    Article  Google Scholar 

  3. Sever P, Beevers G, Bulpitt C, et al. Management guidelines in essential hypertension: report of the second working party of the British Hypertension Society. BMJ 1993; 306: 983–7

    Article  PubMed  CAS  Google Scholar 

  4. Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. The fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC V). Arch Intern Med 1993; 153: 154–83

    Article  Google Scholar 

  5. Kruse W, Rampmaier J, Ullrich G, et al. Patterns of drug compliance with medications to be taken once and twice daily assessed by continuous electronic monitoring in primary care. Int J Clin Pharmacol Ther 1994; 32: 452–7

    PubMed  CAS  Google Scholar 

  6. Eisen SA, Miller DK, Woodward RS, et al. The effect of prescribed daily dose frequency on patient medication compliance. Arch Intern Med 1990; 150: 1881–4

    Article  PubMed  CAS  Google Scholar 

  7. Salient points regarding potassium homeostasis in cardiovascular disease. Drug Ther Perspect 1994 27 Jun; 3: 11–2

  8. Robertson JIS. Guidelines for the treatment of hypertension: a critical review. Cardiovasc Drug Ther 1994; 8: 665–72

    Article  CAS  Google Scholar 

  9. Maharaj B, ven der Byl K. Randomised double-blind comparative study of efficacy and safety of hydroflumethiazide and reserpine and chlortalidone and atenolol in the treatment of mild to moderate hypertension in black patients. J Hum Hypertens 1993; 7: 447–50

    PubMed  CAS  Google Scholar 

  10. Chrysant SG, The Lisinopril-Hydrochlorothiazide Group. Antihypertensive effectiveness of low-dose lisinopril-hydrochlorothiazide combination. A large multicenter study. Arch Intern Med 1994; 154: 737–43

    Article  PubMed  CAS  Google Scholar 

  11. Wilkinson R, Mansy S. A dose finding study of the combination of atenolol and nifedipine in hypertension. Curr Med Res Opin 1990; 12: 108–13

    Article  PubMed  CAS  Google Scholar 

  12. Hort JF, Wilkins HM. Changes in blood pressure, serum potassium and electrolytes with a combination of triamterene and a low dose of chlorthalidone. Curr Med Res Opin 1991; 12: 430–40

    Article  PubMed  CAS  Google Scholar 

  13. Valvo E, Bedogna V, Casagrande P. Ambulatory blood pressure measurement in assessing the antihypertensive effect of benazepril plus hydrochlorothiazide in a fixed combination. Clin Ther 1993; 15: 650–6

    PubMed  CAS  Google Scholar 

  14. Treatment of hypertension in patients with concomitant disorders. Drug Ther Perspect 1994 Nov 14; 4(10): 8–11

    Google Scholar 

  15. Materson BJ, Reda DJ, Cushman WC, et al. Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. N Engl J Med 1993; 328: 914–21

    Article  PubMed  CAS  Google Scholar 

  16. British National Formulary No. 27. London: The Pharmaceutical Press, 1994; 67–82

  17. Chrysant SG, Chappel C, Farnham DJ, et al. Antihypertensive and metabolic effects of single and combined atenolol regimens. J Clin Pharmacol 1992; 32: 61–5

    PubMed  CAS  Google Scholar 

  18. Chrysant SG, Chrysant C, Trus J, et al. Antihypertensive effectiveness of amlodipine in combination with hydrochlorothiazide. Am J Hypertens 1989; 2: 537–41

    PubMed  CAS  Google Scholar 

  19. Chrysant SG, Fox AAL, Stimpel M. Comparison of moexipril — a new ACE inhibitor — to verapamil-SR as add on therapy to low dose hydrochlorothiazide in hypertensive patients. Am J Hypertens 1995 Apr; in press

    Google Scholar 

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Fixed-dose antihypertensive drug combinations may be useful if dual therapy is clinically indicated. Drugs Ther. Perspect 5, 9–10 (1995). https://doi.org/10.2165/00042310-199505080-00004

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