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Controlled release formulations delay and prolong clinical effects following overdose

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References

  1. Buckley NA, Dawson AH, Reith DA. Controlled release drugs in overdose. Drug Saf 1994; 12: 73–84

    Article  Google Scholar 

  2. Baischer W, Wagner A, Seidler D. Carbamazepine poisoning: protracted course with development of gastrointestinal atony and hepatotoxicity [in German]. Wein Klin Wochenschr 1994; 106: 27–9

    CAS  Google Scholar 

  3. Sporer KA, Manning JJ. Massive ingestion of sustained-release verapamil with a concretion and bowel infarction. Ann Emerg Med 1993; 22: 603–5

    Article  PubMed  CAS  Google Scholar 

  4. Bernstein G, Jehle D, Bernaski E. Failure of gastric emptying and charcoal administration in fatal sustained-release theophylline overdose: pharmacobezoar formation. Ann Emerg Med 1992; 21: 1388–90

    Article  PubMed  CAS  Google Scholar 

  5. Spiller HA, Meyers A, Ziemba T, et al. Delayed onset of cardiac arrhythmias from sustained release verapamil. Ann Emerg Med 1991; 20: 201–3

    Article  PubMed  CAS  Google Scholar 

  6. Rankin RJ, Edwards IR. Overdose of sustained release verapamil [letter]. NZ Med J 1990; 103: 165

    CAS  Google Scholar 

  7. McDonald D, Alguire PC. Case report. Fatal overdose with sustained-release verapamil. Am J Med Sci 1992; 303: 115–7

    Article  Google Scholar 

  8. Rankin RJ, Edwards IR. Overdose of sustained release verapamil [letter]. Am J Med Sci 1992; 303: 115–7

    Article  Google Scholar 

  9. Breheny F, McDonagh T, Hackett LP, et al. Disposition and clinical effects of morphine, morphine-6-glucuronide and morphine-3-glucuronide following an intentional overdose of slow release oral morphine in a patient with renal failure. Drug Invest 1993; 6: 291–5

    Article  Google Scholar 

  10. Vale JA, Proudfoot AT. How useful is activated charcoal? BMJ 1993; 306: 78–9

    Article  PubMed  CAS  Google Scholar 

  11. Prescott LF. Drug overdosage and poisoning. In: Speight TM, editor. Avery’s drug treatment. Auckland: ADIS Press, 1987; 283–302

    Google Scholar 

  12. Ellenhorn MJ, Barceloux DG, editors. Medical toxicology. New York: Elsevier, 1988

    Google Scholar 

  13. Tenenbein M. Whole bowel irrigation as a gastrointestinal decontamination procedure after acute poisoning. Med Toxicol 1988; 3: 77–84

    CAS  Google Scholar 

  14. Tenenbein M. Whole bowel irrigation for toxic ingestions. Clin Toxicol 1985; 23(2–3): 177–84

    Article  CAS  Google Scholar 

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Controlled release formulations delay and prolong clinical effects following overdose. Drugs Ther. Perspect 5, 11–13 (1995). https://doi.org/10.2165/00042310-199505070-00005

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