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Optimum Management of the Discharging Ear

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Summary

Discharge from the ear can be the result of many disease processes. The ear may discharge blood, pus, cerebrospinal fluid (CSF) or wax.

Keratosis obturans, stenosis of the external meatus and benign tumours of the external meatus all lead to wax build-up, which may cause recurrent attacks of otitis externa. Malignant tumours, such as basal cell carcinoma, squamous cell carcinoma and tumours of ceruminous gland origin may also present with discharge. Tumours should be excluded by submitting all material removed from the external canal for histological examination.

Single or multiple abscesses (known as furuncles) may occur in the hair follicles in the skin of the external acoustic meatus (EAM). Compulsive scratching, hearing aids and foreign bodies placed in the ear predispose to otitis externa, which is also often associated with infection by Pseudomonas aeruginosa, Staphylococcus aureus and faecal organisms. Management may be with aluminium acetate 14%, topical antibiotic/steroid drops, a gauze wick soaked with icthammol 10% in glycerin or polymyxin B sulphate — neomycin sulphate — hydrocortisone acetate cream placed into the EAM and replaced every 24 to 48 hours, or systemic antibiotics according to severity.

Malignant (necrotising) otitis externa causes progressive destruction of the temporal bone, and cranial nerve palsies (usually facial first). Treatment is limited debridement of infected bone, accompanied by intravenous aminoglycosides, and local antibiotic treatment and aural cleanout or oral ciprofloxacin.

Middle ear conditions causing discharge include acute otitis media, infected grommets, traumatic perforations and chronic suppurative otitis media, as well as tumours of the ear canal skin and middle ear, radiation-induced otitis externa and osteoradionecrosis of the temporal bone, tuberculosis, Langerhans cell histiocytosis, spontaneous or post-traumatic CSF leaks, Wegeners granulomatosis and immune deficiency states.

Topical application of aminoglycoside antibiotics to the middle ear of laboratory animals such as rats, guinea pigs and chinchillas causes sensorineural hearing loss, an effect rarely seen clinically in humans.

If the external acoustic meatus and tympanic membrane are obscured by discharge cotton buds, microsuction equipment or syringing are used to remove it. It is often useful to initiate treatment (usually with topical drops, wicks or an oral antibiotic) with a provisional diagnosis. A full examination and adequate visualisation of the tympanic membrane must eventually be performed, if necessary under anaesthesia, or else serious progressive conditions may be neglected.

The most useful initial investigation is a swab sent for bacteriological assessment; other investigations are usually indicated by clinical findings and the provisional diagnosis.

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References

  • Ajulo SO, Khambata AS, Pushpala SM. Unusual presentation of squamous cell carcinoma of the middle ear and mastoid. Journal of Larngology and Otology 105: 28–40, 1991

    Google Scholar 

  • Alvord LS, Doxey GP, Smith DM. Hearing aids worn with tympanic membrane perforation: complications and solutions. American Journal of Otology 10: 277–280, 1989

    PubMed  CAS  Google Scholar 

  • Bain DJG, Murphy E, Ross F. Acute otitis media: clinical course in children who received a short course of high dose antibiotic. British Medical Journal 291: 1243–1246, 1985

    Article  PubMed  CAS  Google Scholar 

  • Bain J. Justification for antibiotic use in general practice. British Medical Journal 300: 1006–1007, 1990

    Article  PubMed  CAS  Google Scholar 

  • Baker RS, Chole RF. A randomized trial of topical gentamicin after tympanostomy tube placement. Archives of Otolaryngology, Head and Neck Surgery 114: 755–757, 1988

    Article  CAS  Google Scholar 

  • Balkany TJ, Arenberg IK, Steenerson RL. Ventilation tube surgery and middle ear irrigation. Laryngoscope 96: 529–532, 1986

    Article  PubMed  CAS  Google Scholar 

  • Balkany TJ, Barkin RM, Suzuki BH, Watson WJ. A prospective study of infection following tympanostomy and tube insertion. American Journal of Otology 4: 288–291, 1983

    PubMed  CAS  Google Scholar 

  • Bassiouny A, Kamal T, Moawad MK, Hindawy DS. Broad spectrum antifungal agents in otomycosis. Journal of Laryngology and Otology 100: 867–873, 1986

    Article  PubMed  CAS  Google Scholar 

  • Bates GJEM, Drake-Lee AB. Meningitis complicaing acute otitis media. British Medical Journal 296: 532, 1988

    Article  PubMed  CAS  Google Scholar 

  • Becker GD, Eckberg TJ, Goldware RR. Swimming and tympanostomy tubes: a prospective study. Laryngoscope 97: 740–741, 1987

    Article  PubMed  CAS  Google Scholar 

  • Bickerton RC, Roberts C, Little JT. Survey of general practitioners treatment of the discharging ear. British Medical Journal 296: 1649–1650, 1988

    Article  PubMed  CAS  Google Scholar 

  • Bingham BJ, Chevretton E, Firman E. Water contamination and swimming with the open mastoid cavity. Clinical Otolaryngology 13: 347–350, 1988

    Article  PubMed  CAS  Google Scholar 

  • Bingham BJ, Gurr PA, Owen G. Tympanic membrane perforation following the removal of ventilation tubes in the presence of persistent aural discharge. Clinical Otolaryngology 14: 525–528, 1989

    Article  PubMed  CAS  Google Scholar 

  • Bluestone CD. Management of acute otitis media in infants and children: current role of old and new antimicrobial agents. Pediatric Infectious Disease Journal 7: sl29–sl36, 1988

    Google Scholar 

  • Bluestone CD, Paradise JL, Beery QC. Physiology of the eustachian tube in the pathogenesis and management of middle ear effusions. Laryngoscope 82: 1654–1656, 1972

    Article  PubMed  CAS  Google Scholar 

  • Bluestone CD. Current management of chronic suppurative otitis media in infants and children. Pediatric Infectious Disease Journal 7 (Suppl. 11): S137–S140, 1988

    PubMed  CAS  Google Scholar 

  • Browning GG. Childhood otalgia: acute otitis media. British Medical Journal 300: 1005–1006, 1990

    Article  PubMed  CAS  Google Scholar 

  • Browning GG. Medical treatment of chronic mucosal otitis media. Clinical Otolaryngology 9: 141–144, 1984

    Article  PubMed  CAS  Google Scholar 

  • Browning GG, Gatehouse S, Calder IT. The medical management of active chronic otitis media. Journal of Laryngology and Otology 102: 491–495, 1988

    Article  PubMed  CAS  Google Scholar 

  • Browning GG, Picozzi GL, Calder IT, Sweeney G. The medical management of chronic suppurative otitis media. British Medical Journal 287: 1024, 1983

    Article  PubMed  CAS  Google Scholar 

  • Callahan CW. Cost effectiveness of antibiotic therapy for otitis media in a military paediatric clinic. Pediatric Infectious Disease 7: 622–625, 1988

    Article  Google Scholar 

  • Chevretton E, Bingham BJ, Firman E. The prevention of tympanic membrane perforation following the removal of long-term Paparella type II ventilation tubes. Clinical Otolaryngology 12: 377–381, 1987

    Article  PubMed  CAS  Google Scholar 

  • Clayton MI, Osborne JE, Rutherford D, Rivron RP. A double-blind randomised, prospective trial of a topical antiseptic versus a topical antibiotic in the treatment of otorrhea. Clinical Otolaryngology 15: 7–10, 1990

    Article  PubMed  CAS  Google Scholar 

  • Cotton RT. Caution on use of merthiolate in the ear. Correspondence. Journal of Otolaryngology 17: 260, 1988

    Google Scholar 

  • Crowther IA, Simpson D. Medical treatment of chronic otitis media: steroid or antibiotic with steroid ear drops. Clinical Otolaryngology, in press, 1990

  • Cunningham MJ, Curtin HD, Jaffe R, Stool SE. Otologic manifestations of Langerhans’ cell histiocytosis. Archives of Otolaryngology 115: 807–813, 1989

    Article  CAS  Google Scholar 

  • Dekker PJ. Alternative method of application of topical preparations in otitis externa. Journal of Laryngology and Otology 105: 842–843, 1991

    Article  PubMed  CAS  Google Scholar 

  • Dickins JR, Smith JT, Graham SS. Herpes zoster oticus: treatment with intravenous acyclovir. Laryngoscope 98: 776–779, 1988

    Article  PubMed  CAS  Google Scholar 

  • Engelhard D, Cohen D, Strauss N, Sacks TG, Jorczak-Sarni L, et al. Randomised study of myringotomy, amoxycillin/clavulanate, or both for acute otitis media in infants. Lancet 2: 141–143, 1989

    Article  PubMed  CAS  Google Scholar 

  • Freedman A. The efficacy of ceruminolytics. Correspondence. Journal of Otolaryngology 19: 150–151, 1990

    PubMed  CAS  Google Scholar 

  • Gates GA, Avery C, Prihoda TJ, Holt GR. Post-tympanotomy otorrhea. Laryngoscope 96: 630–634, 1986

    Article  PubMed  CAS  Google Scholar 

  • Gates GA, Avery C, Prihoda TJ, Holt GR. Delayed onset of post-tympanotomy otorrhea. Otolaryngology, Head and Neck Surgery 98: 111–115, 1988

    CAS  Google Scholar 

  • Grace A, Grace S. Child abuse within the ear, nose and throat. Journal of Otolaryngology 16: 108–111, 1987

    PubMed  CAS  Google Scholar 

  • Guill MA, Odom RB. Hearing aid dermatitis. Archives of Dermatology 114: 1050–1051, 1978

    Article  PubMed  Google Scholar 

  • Hammond V. Diseases of the external ear. In Kerr AG & Booth JG (Eds) Scott-Brown’s otolaryngology, Vol. 3, 5th ed., pp. 156–171, Butterworth, 1987

  • Hawke M, Wong J, Krajden S. Clinical and microbiological features of otitis externa. Journal of Otolaryngology 13: 289–295, 1984

    PubMed  CAS  Google Scholar 

  • Herdman RCD, Wright JLW. Surgical treatment of obliterative otitis externa. Clinical Otolaryngology 15: 11–14, 1990

    Article  PubMed  CAS  Google Scholar 

  • Hickey SA, Ford GR, O’Connor AF, Eykyn SJ, Sonksen PH. Treating malignant otitis with oral ciprofloxacin. British Medical Journal 299: 550–551, 1989

    Article  PubMed  CAS  Google Scholar 

  • Hu K, Schwarz DW. Electrophysiological evaluation of chloroform-induced inner ear damage. Archives of Otorhinolaryngology 244: 222–228, 1987

    Article  CAS  Google Scholar 

  • Hunsaker DH. Conchomeatoplasty for chronic otitis externa. Archives of Otolaryngology and Head and Neck Surgery 114: 395–398, 1988

    Article  CAS  Google Scholar 

  • Ikeda K, Morizono T, Juhn SK. Cochleotoxicity of otic drops in the chinchilla: a comparative study of Bestron and Cortisporin. American Journal of Otology 12: 429–434, 1991

    Article  PubMed  CAS  Google Scholar 

  • Karma P, Palva T, Kouvalainen K, et al. Finnish approach to the treatment of acute otitis media. Annals of Otology, Rhinology, and Laryngology 94: 1–19, 1985

    Google Scholar 

  • Kent SK, Jones R. Pseudomonas vaccination in chronic ear disease. Journal of Laryngology and Otology 102: 579–581, 1988

    Article  PubMed  CAS  Google Scholar 

  • Kerr AGD, Smyth GDL. Ear trauma. In Kerr AG & Booth JG (Eds) Scott-Brown’s otolaryngology, Vol. 3, 5th ed., pp. 172–184, Butterworth, 1987

  • Klein J. Pneumococcal otitis media vaccination trials. Pediatric Infectious Disease Journal 8: s82–s83, 1989

    Article  PubMed  CAS  Google Scholar 

  • Kwok P, Hawke M. Clotrimazole powder in the treatment of otomycosis. Journal of Otolaryngology 16: 398, 1987

    PubMed  CAS  Google Scholar 

  • Leach JL, Wright CG, Edwards LB, Meyerhoff WM. Effect of topical fosfomycin on polymyxin B ototoxicity. Archives of Otolaryngology, Head and Neck Surgery 116: 49–53, 1990

    Article  CAS  Google Scholar 

  • Lindeman P, Tengstrand T. Clinical experience with the bone-anchored hearing aid. Scandinavian Audiology 16: 37–41, 1987

    Article  PubMed  CAS  Google Scholar 

  • Liston SL, Siegel LG. Tinactin in the treatment of fungal otitis externa. Laryngoscope 96: 699, 1986

    Article  PubMed  CAS  Google Scholar 

  • Ludman H. Otitis externa. In Mawson’s diseases of the ear, 5th ed., chapter 14, pp. 322–355, Edward Arnold, 1988

  • Luxford WM, Sheehy JL. Myringotomy and ventilation tubes: a report of 1,568 ears. Laryngoscope 92: 1293–1297, 1982

    Article  PubMed  CAS  Google Scholar 

  • Makela PH, Karma K. Vaccination trials in otitis media: experiences in Finland since 1977. Pediatric Infectious Disease Journal 8: s79–s82, 1989

    Article  PubMed  CAS  Google Scholar 

  • Marks NJ. Secretory otitis media: grommets and swimming. Clinical Otolaryngology 10: 1–2, 1985

    Article  PubMed  CAS  Google Scholar 

  • McKelvie P, Johnstone L, Jamieson L, Brooks C. The effect of gentamycin drops on the cochlea. British Journal of Audiology 9: 45–47, 1975

    Article  Google Scholar 

  • Moffat D. Ototoxicity. In Kerr AG & Booth JG (Eds) Scott-Brown’s otolaryngology, 5th ed., Vol. 3, pp. 465–499, Butterworth, 1987

  • Morizono T, Paparella MM, Juhn SL. Ototoxicity of propylene glycol in experimental animals. American Journal of Otolaryngology 1: 393–399, 1980

    Article  PubMed  CAS  Google Scholar 

  • Mugliston T, O’Donoghue G. Otomycosis: a continuing problem. Journal of Laryngology and Otology 99: 327–333, 1985

    Article  PubMed  CAS  Google Scholar 

  • Nunez DA, Browning GG. Risks of developing an otogenic cranial abscess. Journal of Otology and Laryngology 104: 468–472, 1990

    Article  CAS  Google Scholar 

  • Paulose KO, Al Khalifa S, Shenoy P, Sharma RK. Mycotic infection of the ear (otomycosis): a prospective study. Journal of Laryngology and Otology 103: 30–35, 1989

    Article  PubMed  CAS  Google Scholar 

  • Piccirillo JF, Parnes SM. Ciprofloxacin for the treatment of chronic ear disease. Laryngoscope 99: 510–513, 1989

    PubMed  CAS  Google Scholar 

  • Podoshin L, Fradis M, Ben David J. Ototoxicity of ear drops in patients suffering from chronic otitis media. Journal of Otology and Laryngology 103: 46–50, 1989

    Article  CAS  Google Scholar 

  • Premachandra DJ, Woodward BM, Milton CM, Sergeant RJ, Fabre JW. Treatment of postoperative otorrhea by grafting of mastoid cavities with cultured autologous skin cells. Lancet 335: 365–367, 1990

    Article  PubMed  CAS  Google Scholar 

  • Reilly G, Skinner DW. Antibiotic/steroid drop preparations: a cost effective approach to their use. Journal of Laryngology and Otology 104: 862–864, 1990

    Article  PubMed  CAS  Google Scholar 

  • Robinson AC, Hawke M. The efficacy of ceruminolytics: everything old is new again. Journal of Otolaryngology 18: 263–267, 1989

    PubMed  CAS  Google Scholar 

  • Robinson AC. Management of radiation induced otitis externa. Journal of Laryngology and Otology 104: 458–459, 1990

    Article  PubMed  CAS  Google Scholar 

  • Robinson PM. Contact hypersensitivity to gentamicin-hydrocor-tisone ear drops. Journal of Laryngology and Otology 102: 577–578, 1988

    Article  PubMed  CAS  Google Scholar 

  • Robinson AC. Evaluation for waterproof ear protectors in swimmers. Journal of Laryngology and Otology 103: 1154–1157, 1989

    Article  PubMed  CAS  Google Scholar 

  • Sabater F, Mensa J, Domenech J, Lonca M, Carulla M. Necrotising external otitis treated with ciprofloxacin. Journal of Laryngology and Otology 102: 606–607, 1988

    Article  PubMed  CAS  Google Scholar 

  • Senturia BH, Marcus MD, Lucente FE. Diseases of the external ear, 2nd ed., chapter 4, pp. 31–76, Grune & Stratton, New York, 1980

  • Shenoi PM. The medical management of chronic suppurative otitis media. In Kerr AG & Booth JG (Eds) Scott-Brown’s otolaryngology, 5th ed., Vol. 3, pp. 215–237, Butterworth, 1987

  • Slack RW. A study of three preparations in the treatment of otitis externa. Journal of Laryngology and Otology 101: 533–535, 1987

    Article  PubMed  CAS  Google Scholar 

  • Smith IM, Keay DG, Buxton PK. Contact hypersensitivity in patients with chronic otitis externa. Clinical Otolaryngology 15: 155–158, 1990

    Article  PubMed  CAS  Google Scholar 

  • Smith RB, Moodie J. Comparative efficacy and tolerability of 2 antibacterial and anti-inflammatory preparations (“Otomise” spray and “Otosporin” ear drops) in the treatment of otitis externa. Current Medical Research and Opinion 11: 661–667, 1990

    Article  PubMed  CAS  Google Scholar 

  • Spandow O, Hellstrom S, Anniko M. Impaired hearing following instillation of hydrocortisone into the middle ear: preliminary report from an animal study. Acta Otolaryngologica (Suppl. 455): 90–93, 1988

  • Stenfors LE. Repair of tympanic membrane with hyaluronic acid: an alternative to myringoplasty. Journal of Otology and Laryngology 103: 39–40, 1989

    Article  CAS  Google Scholar 

  • van Buchem FL, Dunk JHM, van’t Hoft MA. Therapy of acute otitis media: myringotomy, antibiotics, neither? Lancet 2: 883–887, 1981

    Article  PubMed  Google Scholar 

  • van Buchem FL, Peeter MF, van’t Hof MA. Acute otitis media. British Medical Journal 290: 1033–1037, 1985

    Article  PubMed  Google Scholar 

  • Vartiainen E, Karjalainen S. Factors influencing sensorineural hearing loss in chronic otitis media. American Journal of Otolaryngology 8: 13–15, 1987

    Article  PubMed  CAS  Google Scholar 

  • Vassalli L, Harris DM, Gradini R, Applebaum EL. Propylene gly-col-induced cholesteatoma in chinchilla middle ears. American Journal of Otolaryngology 9: 180–188, 1988

    Article  PubMed  CAS  Google Scholar 

  • Vomero E, Ratner SJ. Diagnosis of miliary tuberculosis by examination of middle ear discharge. Archives of Otolaryngology 114: 1029–1030, 1988

    Article  CAS  Google Scholar 

  • Wilson PS. Distribution of ear drops in the normal ear. Journal of Laryngology and Otology 105: 359–362, 1991

    Article  PubMed  CAS  Google Scholar 

  • Wilson PS, Dingle A, Grocutt M, Reid AP. Distribution of ear drops using a non-aerosol delivery system. Journal of Laryngology and Otology 105: 651–652, 1991

    Article  PubMed  CAS  Google Scholar 

  • Wright CG, Halama AR, Meyerhoff WL. Ototoxicity of an ototopical preparation in a primate. American Journal of Otology 8: 56–60, 1987

    PubMed  CAS  Google Scholar 

  • Yaniv E. Tuberculous otitis media as a secondary infection to chronic otitis media with cholesteatoma. American Journal of Otology 8: 40–42, 1987

    Article  PubMed  CAS  Google Scholar 

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Ruddy, J., Bickerton, R.C. Optimum Management of the Discharging Ear. Drugs 43, 219–235 (1992). https://doi.org/10.2165/00003495-199243020-00008

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