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Guidelines for Treating Hypertension in the Elderly

  • Practical Therapeutics
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Summary

The incidence of hypertension increases with ageing, and one-third of the elderly population is affected. The role of hypertension as a cardiovascular risk factor has been confirmed in the elderly by the incidence of stroke and myocardial infarction. Effective treatment of hypertension significantly reduces the risk of associated complications: cardiovascular death, congestive heart failure and stroke.

There are numerous secondary effects of antihypertensive treatment and the prescription and monitoring of treatment should take into account potential effects specific to elderly patients.

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References

  • Amery A, Birkenhager W, Brixko W, Bulpitt C, Clement D, et al. Efficacy of antihypertensive drug treatment according to age, sex, blood pressure and previous cardiovascular disease in patients over the age of 60. Lancet 2: 589–592, 1986

    Article  PubMed  CAS  Google Scholar 

  • Australian National Blood Pressure Study Management Committee. The Australian therapeutic trial in mild hypertension. Lancet 1: 1261–1267, 1980

    Google Scholar 

  • Bühler FR. Antihypertensive treatment according to age, plasma renin and race. Drugs 35: 495–503, 1988

    Article  PubMed  Google Scholar 

  • CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). New England Journal of Medicine 316: 1429–1435, 1987

    Article  Google Scholar 

  • DiBianco R. Adverse reactions with angiotensin converting enzyme (ACE) inhibitors. Medical Toxicology 1: 122–141, 1986

    PubMed  CAS  Google Scholar 

  • Frishmann WH, Charlap S, Michelson EL. Calcium channel blockers in systemic hypertension. American Journal of Cardiology 58: 157–160, 1986

    Article  Google Scholar 

  • Hulley BS, Furberg CD, Gurland B, McDonald R, Perry HM, et al. Systolic hypertension in the elderly program (SHEP): antihypertensive efficacy of chlorthalidone. American Journal of Cardiology 56: 913–920, 1985

    Article  PubMed  CAS  Google Scholar 

  • Hypertension Detection and Follow Up Program Cooperative Group. Five-year findings of the hypertension detection and follow up program: mortality by race, sex and age. Journal of the American Medical Association 242: 2572–2577, 1979

    Article  Google Scholar 

  • IPPPSH Collaborative Group. Cardiovascular risk and risk factors in a randomized trial of treatment based on the beta-blocker oxprenolol: the international prospective primary prevention study in hypertension (IPPPSH). Journal of Hypertension 3: 379–392, 1985

    Article  Google Scholar 

  • Kannel WB. Role of blood pressure in cardiovascular disease: the Framingham Study. Angiology 26: 1–14, 1975

    Article  PubMed  CAS  Google Scholar 

  • Kannel WB. Implication of Framingham study data for treatment of hypertension: impact of other risk factors. In Laragh JH, et al. (Eds) Frontiers in hypertension research, pp. 17–21, Springer-Verlag, New York, 1981

    Chapter  Google Scholar 

  • Kannel WB, Sorlie R, Castelli WP, McGee D. Blood pressure and survival after myocardial infarction: the Framingham Study. American Journal of Cardiology 45: 326–330, 1980

    Article  PubMed  CAS  Google Scholar 

  • Kannel WB, Gordon T. Cardiovascular risk factors in the aged: the Framingham study in epidemiology of aging. NIH Publication no. 80 969, pp. 65–89, National Institute of Aging, Bethesda, 1980

    Google Scholar 

  • Lant A. Diuretics. Clinical pharmacology and therapeutic use (part II). Drugs 29: 162–188, 1985

    Article  PubMed  CAS  Google Scholar 

  • Lewis RV, McDevitt DG. Adverse reactions and interactions with β-adrenoceptor blocking drugs. Medical Toxicology 1: 343–361, 1986

    PubMed  CAS  Google Scholar 

  • Leishman AW. Merits of reducing high blood pressure. Lancet 1: 1984–1988, 1963

    Google Scholar 

  • McLachlan MJ. The aging kidney. Lancet 2: 143–147, 1978

    Article  PubMed  CAS  Google Scholar 

  • Medical Research Council Working Party. MRC trial of treatment of hypertension: principal results. British Medical Journal 291: 97–104, 1985

    Article  Google Scholar 

  • Messerli FM, Dreslinski GR, Husserl FE. Antiadrenergic therapy: special aspects of hypertension in the elderly. Hypertension 3 (Suppl. 2): 226–229, 1981

    Google Scholar 

  • Miller HW. National Center of Health Statistics: plan and operation of the National Health and Nutrition Examination Survey: United States 1971–1973, pp. 1–46, Government Printing Office, Washington DC, 1973

    Google Scholar 

  • Okun R. Effectiveness of prazosin as initial antihypertensive therapy. American Journal of Cardiology 51: 644–650, 1983

    Article  PubMed  CAS  Google Scholar 

  • Ostfeld AM, Shekelle RB, Klawars H, Tuffo HM. Epidemiology of stroke in an elderly welfare population. American Journal of Public Health 64: 450–458, 1974

    Article  PubMed  CAS  Google Scholar 

  • Pickering G. Hypertension: definition, natural history and consequences. American Journal of Medicine 52: 570–576, 1972

    Article  PubMed  CAS  Google Scholar 

  • Pooling Project Research Group. Relationship of blood pressure, serum cholesterol, smoking, relative weight and ECG abnormalities to incidence of major coronary events: final report of the pooling project. Journal of Chronic Diseases 31: 201–306, 1978

    Article  Google Scholar 

  • Shekelle RB, Ostfeld A, Awans HL. Hypertension and risk of stroke in an elderly population. Stroke 5: 71–75, 1974

    Article  PubMed  CAS  Google Scholar 

  • Simon A. Hypertension artérielle essentielle: stratégie d’emploi des médicaments antihypertenseurs. Revue de Médecine Interne 7: 432–441, 1986

    Google Scholar 

  • Smirk FH, Alstad L. Treatment of arterial hypertension by penta and exaurethorium salts based on 150 tests on hypertensives of varied aetiology and 53 patients for a period of 2 to 14 months. British Medical Journal June 2: 1217–1228, 1951

    Article  Google Scholar 

  • Veterans’ Administration Cooperative Study Group on Anti-hypertensive Agents, Effects of treatment on morbidity in hypertension: results in patients with diastolic blood pressures averaging 115 through 129mm Hg. Journal of the American Medical Association 202: 1028–1034, 1967

    Article  Google Scholar 

  • Veterans’ Administration Cooperative Study Group on Anti-hypertensive Agents. Effects of treatment on morbidity in hypertension. Influence of age, diastolic pressure and cardiovascular disease: further analysis of side effects. Circulation 45: 991–1004, 1972

    Article  Google Scholar 

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Emeriau, JP. Guidelines for Treating Hypertension in the Elderly. Drugs 38, 612–620 (1989). https://doi.org/10.2165/00003495-198938040-00007

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  • DOI: https://doi.org/10.2165/00003495-198938040-00007

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