Abstract
The recent findings of the Hypertension Detection and Follow-up Program (HDFP) extend the evidence that early detection and control of hypertension can substantially reduce cardiovascular morbidity and mortality and prolong life (1). In particular, it has now been demonstrated that treatment of even mild degrees of hypertension (i.e., 90–104 mmHg diastolic pressure) can reduce cardiovascular sequelae. Furthermore, it has been shown that more rigorous goals pay dividends in a greater reduction in mortality. This finding is quite consistent with epidemiologic data from Framingham, which have indicated a continuum of risk with a 30% increment for each 10-mmHg increase in pressure throughout the blood pressure range and including “normotensive” values (Fig. 1). This has indicated that the lower the pressure, the lower the risk, even within the borderline or normal range.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Hypertension Detection and Follow-up Program Cooperative Group (1979) Five-year findings of the Hypertension Detection and Follow-up Program: I. Reduction in mortality of persons with high blood pressure, including mild hypertension. JAMA 242: 2562–2571
Kannel WB, Dawber TR (1974) Hypertension as an ingredient of a cardiovascular risk profile. Br J Hosp Med 2: 508–524
Apostilides A, Blaufox MD, Borhani NO, Cutter G, Daugherty S, Lewin AJ, Polk BF (1979) Mild Hypertensives in the Hypertension Detection and Follow-up Program. Ann NY Acad Sci 304: 254–266
Veterans Administration Cooperative Study Group on Antihypertensive Agents (1967) Effects of treatment on morbidity in hypertension: I. Results in patients with diastolic blood pressures averaging 115- 129 mmHg. JAMA 202: 1028 - 1034
Koch-Weser J (1973) The therapeutic challenge of systolic hypertension. N Engl J Med 289: 481
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1981 Springer-Verlag New York Inc.
About this paper
Cite this paper
Kannel, W.B. (1981). Implications of Framingham Study Data for Treatment of Hypertension: Impact of Other Risk Factors. In: Laragh, J.H., Bühler, F.R., Seldin, D.W. (eds) Frontiers in Hypertension Research. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5899-5_4
Download citation
DOI: https://doi.org/10.1007/978-1-4612-5899-5_4
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-5901-5
Online ISBN: 978-1-4612-5899-5
eBook Packages: Springer Book Archive