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Matrix-assisted Laser Desorption Ionization Mass Spectrometry of Maltohexaose and Acetylsalicylic Acid Using Alkali Metal Cation-substituted Zeolites

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Abstract

Using alkali-metal cation-substituted zeolites and 2,4,6-trihydroxyacetophenone (THAP), which is a typical organic matrix molecule for matrix-assisted laser desorption ionization (MALDI), mass spectrometry has been performed for maltohexaose and acetylsalicylic acid, and the cation-selective ionization of these analytes was achieved. It is found that a complex of cation-substituted zeolite and THAP can be applicable to a compound that is hard to be ionized by a proton adduction in conventional MALDI.

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Authors and Affiliations

  1. Department of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo, 192–0397, Japan

    Junya Suzuki & Tatsuya Fujino

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  1. Junya Suzuki
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  2. Tatsuya Fujino
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Correspondence to Tatsuya Fujino.

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Suzuki, J., Fujino, T. Matrix-assisted Laser Desorption Ionization Mass Spectrometry of Maltohexaose and Acetylsalicylic Acid Using Alkali Metal Cation-substituted Zeolites. ANAL. SCI. 28, 901–904 (2012). https://doi.org/10.2116/analsci.28.901

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  • DOI: https://doi.org/10.2116/analsci.28.901

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