Abstract
Objective: To study the relationship between cholecystolithiasis and polypoid gallbladder(PLG), 260 patients with polypoid gallbladder were investigated. The patients were divided into 2 groups: group A (PLG combined with cholecystolithiasis) and group B (without cholecystolithiasis). The clinical pathological characteristics were analyzed. The intestinal epithelium metaplasia and atypical hyperplasia of the gallbladder mucosa were observed under light microscope. Results: Intestinal epithelium metaplasia and atypical hyperplasia of gallbladder mucosa were found in 47 of the 260 cases. The pathological lesions included 16 gallbladder carcinoma, 11 adenomatosis polyp, 5 myoadenoma, 7 cholesterol polyp, 4 inflammatory polyp and 4 adenomatosis hyperplasia, which occurred in 26 and 21 patients in group A and group B, i. e. 44.0% and 10.3% respectively. The difference between group A and group B was statistically significant (P<0.01). Conclusion: Cholecystolithiasis and the succeeding inflammatory reaction is a risk-factor for the polypoid gallbladder to develop tumour.
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References
Cheng, G. H., Sui, J. P. and Zhu, Z. L., 1997. Excision of gallbladder polyp by microwave through bile tract endoscope.J. Chin Hepatobiliary surg, (5):276–277.
Duarte, I., Lianos, O. and Domake, H., 1997. The metaplasia and precursor lesion of gallbladder carcinoma.Cancer,72(6): 1878–1884.
Huang, H., Sheng, Y.M., Qiu, M., Zheng, C. Z., Ke, C. W., Li, J. H. and Hua, J. D., 1996. 112 cases polypoid gallbladder were exercised under laparoscope.J Chin Prac Surg,16(1): 34–35.
Ju, J. Q., 2000. The experience in treatment of 25 cases gallbladder myoadeno hyperplasia,J Chin Prac Surg,20(10): 636.
Li, J.J., Liu, S. B. and Cheng, D. D., 1997. The study of the relationship of pathological lesion of gallbladder mucosa and gallbladder carcinoma.J Chin Prac Surg,17(5): 275–277.
Si, J. S. and Yang, Y. J., 2000. The process in the research of the relationship between primary gallbladder carcinoma and cholecystolithiasis.J Chin Gen Surg,15 (6): 373.
Wu, J. S., He, X. L., Gao, D. M., Ma, Q. J. and Fu J., 2000. Analysis of 109 cases polypoid gallbladder.J Chin Prac Surg,20(2): 104–106.
Zhang, X. B., Zhang, G. J., Liu, M., Hou, H. L. and Gong, F. Q., 1994. Gallbladde mucosa hyperplasia and gallbladder carcinoma.Shanxi Medicine Journal,23(2): 111–113(in Chinese).
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Project (No. 2002ZXO19) supported by the Zhejiang Province Health Bureau, China
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Ai-jiao, W., Ying-qi, L. & Li-an, D. Relationship between cholecystolithiasis and polypoid gallbladder. J. Zhejiang Univ. Sci. A 4, 620–622 (2003). https://doi.org/10.1631/jzus.2003.0620
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DOI: https://doi.org/10.1631/jzus.2003.0620