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Microstructural, mechanical and biocompatibility investigation of metal–polymer-doped hydroxyapatite

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Abstract

The present work describes about doping of polyvinyl alcohol (PVA) in hydroxyapatite (HAp) along with magnesium (Mg2+) and zinc (Zn2+) ions. The incorporation of the dopants into the HAp matrix has been studied by X-ray diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM), Fourier Transform Infrared (FTIR) and Raman spectroscopy. Corrosion resistance, impedance, size and volume of the pores, thrombogenicity and hardness were also investigated. Its potential for better biomedical applications is highlighted by changes in surface shape, increased crystallite size, improved hardness, decreased clotting tendency, decreased corrosion and modified electrical characteristics. These results imply that, in comparison with pure HAp, the synthesized composite material possesses better physical, mechanical, electrical and biological characteristics. These changes may have a major effect on biomedical applications, in particular when it relates to developing superior biomaterials for hard tissue implants.

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Acknowledgments

Authors thank all Central Instruments Facility (CIF) staffs for providing the data.

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Authors and Affiliations

  1. Department of Chemistry, Birla Institute of Technology, Mesra, Ranchi, 835215, Jharkhand, India

    Anuradha Mahanty & Deep Shikha

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  1. Anuradha Mahanty
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  2. Deep Shikha
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Dr. DS gave the concept and AM was involved in the synthesis, experimental work and paper writing. Finally, data analysis and editing were done by Dr. DS.

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Correspondence to Deep Shikha.

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Mahanty, A., Shikha, D. Microstructural, mechanical and biocompatibility investigation of metal–polymer-doped hydroxyapatite. Journal of Materials Research 39, 1128–1138 (2024). https://doi.org/10.1557/s43578-024-01297-6

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