Skip to main content
SpringerLink
Log in

Biodegradable materials and devices for neuroelectronics

  • Review Article
  • Published:
MRS Bulletin Aims and scope Submit manuscript

Abstract

Recent advances in biodegradable neuroelectronics, which remove the need for extraction surgery and reduce foreign body reactions, provide versatile options for implantable devices, such as for provisional diagnosis and acute treatment. The electrical interface of neuroelectronics is a key technology for the acquisition and delivery of precisely controlled signals. Herein, we describe the hydrolysis mechanisms of candidate electrode materials and their properties for use in biodegradable neuroelectronic devices. Additionally, we discuss the challenges and strategies for increasing the long-term stability of electrodes. Finally, we summarize recent applications of biodegradable neuroelectronic devices for the diagnosis and treatment of neural disorders.

Graphical abstract

Schematics of biodegradable materials and devices for neuroelectronic applications. Reproduced with permission from Reference 12. © 2016 Nature Publishing Group/; Reference 27. © 2013 Wiley; Reference 49. © 2020 AAAS; Reference 56. © 2019 Wiley; Reference 59. © 2022 Wiley; Reference 83. © 2019 AAAS.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2
Figure 3
Figure 4

Similar content being viewed by others

References

  1. P. Jastrzebska-Perfect, S. Chowdhury, G.D. Spyropoulos, Z. Zhao, C. Cea, J.N. Gelinas, D. Khodagholy, Adv. Funct. Mater. 30, 1909165 (2020)

    Article  CAS  Google Scholar 

  2. K. Jackowska, P. Krysinski, Anal. Bioanal. Chem. 405, 3753 (2013)

    Article  CAS  Google Scholar 

  3. C. Zhao, K.M. Cheung, I.-W. Huang, H. Yang, N. Nakatsuka, W. Liu, Y. Cao, T. Man, P.S. Weiss, H.G. Monbouquette, A.M. Andrews, Sci. Adv. 7(48), eabj7422 (2021). https://doi.org/10.1126/sciadv.abj7422

    Article  Google Scholar 

  4. B. Wang, X. Wen, Y. Cao, S. Huang, H.A. Lam, P.S. Chung, H.G. Monbouquette, P.Y. Chiou, N.T. Maidment, Lab Chip 20, 1390 (2020)

    Article  CAS  Google Scholar 

  5. D.W. Park, J.P. Ness, S.K. Brodnick, C. Esquibel, J. Novello, F. Atry, D.H. Baek, H. Kim, J. Bong, K.I. Swanson, A.J. Suminski, K.J. Otto, R. Pahaie, J.C. Williams, Z. Ma, ACS Nano 12, 148 (2018)

    Article  CAS  Google Scholar 

  6. X.L. Chu, X.Z. Song, Q. Li, Y.R. Li, F. He, X.S. Gu, D. Ming, Neural Regen. Res. 17, 2185 (2022)

    Article  Google Scholar 

  7. G. Lee, E. Ray, H.-J. Yoon, S. Genovese, Y.S. Choi, M.-K. Lee, A. Şahin, Y. Yan, H.-Y. Ahn, A.J. Bandodkar, J. Kim, M. Park, H. Ryu, S.S. Kwak, Y.H. Jung, A. Odabas, U. Khandpur, W.Z. Ray, M.R. MacEwan, J.A. Rogers, Sci. Adv. 8(40), eabp9169 (2022). https://doi.org/10.1126/sciadv.abp9169

    Article  Google Scholar 

  8. J.T. Reeder, Z. Xie, Q. Yang, M.H. Seo, Y. Yan, Y. Deng, K.R. Jinkins, S.R. Krishnan, C. Liu, S. Mckay, E. Patnaude, A. Johnson, Z. Zhao, M.J. Kim, Y. Xu, I. Huang, R. Avila, C. Felicelli, E. Ray, X. Guo, W.Z. Ray, Y. Huang, M.R. Macewan, J.A. Rogers, Science 377, 109 (2022)

    Article  CAS  Google Scholar 

  9. M.B. Christensen, S.M. Pearce, N.M. Ledbetter, D.J. Warren, G.A. Clark, P.A. Tresco, Acta Biomater. 10, 4650 (2014)

    Article  CAS  Google Scholar 

  10. S.K. Kang, L. Yin, C. Bettinger, MRS Bull. 45(2), 87 (2020)

    Article  CAS  Google Scholar 

  11. J.S. Shim, J.A. Rogers, S.K. Kang, Mater. Sci. Eng. R 145, 100624 (2021)

    Article  Google Scholar 

  12. S.K. Kang, R.K. Murphy, S.W. Hwang, S.M. Lee, D.V. Harburg, N.A. Krueger, J. Shin, P. Gamble, H. Cheng, S. Yu, Z. Liu, J.G. McCall, M. Stephen, H. Ying, J. Kim, G. Park, R.C. Webb, C.H. Lee, S. Chung, D.S. Wie, A.D. Gujar, B. Vemulapalli, A.H. Kim, K.M. Lee, J. Cheng, Y. Huang, S.H. Lee, P.V. Braun, W.Z. Ray, J.A. Rogers, Nature 530, 71 (2016)

    Article  CAS  Google Scholar 

  13. J. Koo, M.R. MacEwan, S.K. Kang, S.M. Won, M. Stephen, P. Gamble, Z. Xie, Y. Yan, Y.Y. Chen, J. Shin, N. Birebaum, S. Chung, S.B. Kim, J. Khalifeh, D.V. Harburg, K. Bean, M. Paskett, J. Kim, Z.S. Zohny, S.M. Lee, R. Zhang, K. Luo, B. Ji, A. Banks, H.M. Lee, Y. Huang, W.Z. Ray, J.A. Rogers, Nat. Med. 24, 1830 (2018)

    Article  CAS  Google Scholar 

  14. W. Bai, J. Shin, R. Fu, I. Kandela, D. Lu, X. Ni, Y. Park, Z. Liu, T. Hang, D. Wu, Y. Liu, C.R. Haney, I. Stepien, Q. Yang, J. Zhao, K.R. Nandoliya, H. Zhang, X. Sheng, L. Yin, K. MacRenaris, A. Brikha, F. Aird, M. Pezhouh, J. Hornick, W. Zhou, J.A. Rogers, Nat. Biomed. Eng. 3, 644 (2019)

    Article  Google Scholar 

  15. S.-W. Hwang, H. Tao, D.-H. Kim, H. Cheng, J.-K. Song, E. Rill, M.A. Brenckle, B. Panilaitis, S.M. Won, Y.-S. Iim, K.J. Yu, A. Ameen, R. Li, Y. Su, M. Yang, D.L. Kaplan, M.R. Zakin, M.J. Slepian, Y. Huang, F.G. Omenetto, J.A. Rogers, Science 337(6102), 1640 (2012)

    Article  CAS  Google Scholar 

  16. G.T. Go, Y. Lee, D.G. Seo, T.W. Lee, Adv. Mater. 34, 2201864 (2022)

    Article  CAS  Google Scholar 

  17. Y.S. Choi, Y.Y. Hsueh, J. Koo, Q. Yang, R. Avila, B. Hu, Z. Xie, G. Lee, Z. Ning, C. Liu, Y. Xu, Y.J. Lee, W. Zhao, J. Fang, Y. Deng, S.M. Lee, A. Vázquez-Guardado, I. Stepien, Y. Yan, J.W. Song, C. Haney, Y.S. Oh, W. Liu, H.J. Yoon, A. Banks, M.R. MacEwan, G.A. Ameer, W.Z. Ray, Y. Huang, T. Xie, C.K. Franz, S. Li, J.A. Rogers, Nat. Commun. 11, 5990 (2020)

    Article  CAS  Google Scholar 

  18. Y.S. Choi, J. Koo, Y.J. Lee, G. Lee, R. Avila, H. Ying, J. Reeder, L. Hambitzer, K. Im, J. Kim, K.-M. Lee, J. Cheng, Y. Huang, S.-K. Kang, J.A. Rogers, Adv. Funct. Mater. 30(31), 2000941 (2020)

    Article  CAS  Google Scholar 

  19. J. Deng, H. Yuk, J. Wu, C.E. Varela, X. Chen, E.T. Roche, C.F. Guo, X. Zhao, Nat. Mater. 20(2), 229 (2021)

    Article  CAS  Google Scholar 

  20. C. Yang, Z. Suo, Nat. Rev. Mater. 3, 125 (2018)

    Article  CAS  Google Scholar 

  21. S.K. Kang, S.W. Hwang, H. Cheng, S. Yu, B.H. Kim, J.H. Kim, Y. Huang, J.A. Rogers, Adv. Funct. Mater. 24, 4427 (2014)

    Article  CAS  Google Scholar 

  22. J.Y. Gao, Anal. Chem. 84, 10671 (2012)

    Article  CAS  Google Scholar 

  23. Y. Hattori, Y. Haruna, M. Otsuka, Colloids Surf. B 102, 227 (2013)

    Article  CAS  Google Scholar 

  24. D.H. Davies, G.T. Burstein, Corrosion 36, 416 (1980)

    Article  CAS  Google Scholar 

  25. V. Fournier, P. Marcus, I. Olefjord, Surf. Interface Anal. 34, 494 (2002)

    Article  CAS  Google Scholar 

  26. P.V. Danckwerts, Trans. Faraday Soc. 46, 300 (1950)

    Article  CAS  Google Scholar 

  27. R. Li, H. Cheng, Y. Su, S.W. Hwang, L. Yin, H. Tao, M.A. Brenckle, D.H. Kim, F.G. Omenetto, J.A. Rogers Y. Huang, Adv. Funct. Mater. 23, 3106 (2013)

    Article  CAS  Google Scholar 

  28. L. Yin, H. Cheng, S. Mao, R. Haasch, Y. Liu, X. Xie, S.W. Hwang, J. Harshvardhan, S.K. Kang, Y. Su, R. Li, Y. Huang, J.A. Rogers, Adv. Funct. Mater. 24, 645 (2014)

    Article  CAS  Google Scholar 

  29. S.W. Hwang, G. Park, C. Edwards, E.A. Corbin, S.K. Kang, H. Cheng, J.K. Song, J.H. Kim, S. Yu, J. Ng, J.E. Lee, J. Kim, C. Yee, B. Bhaduri, Y. Su, F.G. Omennetto, Y. Huang, R. Bashir, L. Goddard, G. Popescu, K.M. Lee, J.A. Rogers, ACS Nano 8, 5843 (2014)

    Article  CAS  Google Scholar 

  30. L. Yin, A.B. Farimani, K. Min, N. Vishal, J. Lam, Y.K. Lee, N.R. Aluru, J.A. Rogers, Adv. Mater. 27, 1857 (2015)

    Article  CAS  Google Scholar 

  31. Y.K. Lee, K.J. Yu, E. Song, A. Barati Farimani, F. Vitale, Z. Xie, Y. Yoon, Y. Kim, A. Richardson, H. Luan, Y. Wu, X. Xie, T.H. Lucas, K. Crawford, Y. Mei, X. Feng, Y. Huang, B. Litt, N.R. Aluru, L. Yin, J.A. Rogers, ACS Nano 11, 12562 (2017)

    Article  CAS  Google Scholar 

  32. H. Seidel, L. Csepregi, A. Heuberger, H. Baumgärtel, J. Electrochem. Soc. 137, 3612 (1990)

    Article  CAS  Google Scholar 

  33. P.S. Sidhu, R.J. Gilkes, R.M. Cornell, A.M. Posner, J.P. Quirk, Clays Clay Miner. 29, 269 (1981)

    Article  CAS  Google Scholar 

  34. J. Xu, H. Lee, Chemosensors 8, 66 (2020)

    Article  CAS  Google Scholar 

  35. G.G. Perrault, J. Electroanal. Chem. Interfacial Electrochem. 51, 107 (1974)

    Article  CAS  Google Scholar 

  36. L. Lei, Y. Sun, X. Wang, Y. Jiang, J. Li, Front. Mater. 7, 96 (2020)

    Article  Google Scholar 

  37. X. Dong, B. Wei, D. Legut, H. Zhang, R. Zhang, Phys. Chem. Chem. Phys. 23, 19602 (2021)

    Article  CAS  Google Scholar 

  38. K. Xi, Y. Gu, J. Tang, H. Chen, Y. Xu, L. Wu, F. Cai, L. Deng, H. Yang, Q. Shi, W. Cui, L. Chen, Nat. Commun. 11, 4504 (2020)

    Article  CAS  Google Scholar 

  39. W.F. Ng, K.Y. Chiu, F.T. Cheng, Mater. Sci. Eng. C 30, 898 (2010)

    Article  CAS  Google Scholar 

  40. M. Anik, K. Osseo-Asare, J. Electrochem. Soc. 149, B224 (2002)

    Article  CAS  Google Scholar 

  41. I. Johnson, W. Jiang, H. Liu, Sci. Rep. 7, 14335 (2017)

    Article  Google Scholar 

  42. M. Talha, Y. Ma, P. Kumar, Y. Lin, A. Singh, Colloids Surf. B 176, 494 (2019)

    Article  CAS  Google Scholar 

  43. A. Schauer, C. Redlich, J. Scheibler, G. Poehle, P. Barthel, A. Maennel, V. Adams, T. Weissgaeber, A. Linke, P. Quadbeck, Materials (Basel) 14, 7776 (2021)

    Article  CAS  Google Scholar 

  44. A. Yamamoto, S. Hiromoto, Mater. Sci. Eng. C 29, 1559 (2009)

    Article  CAS  Google Scholar 

  45. C. Crimu, G. Bolat, C. Munteanu, D. Mareci, Mater. Corros. 66, 649 (2015)

    Article  CAS  Google Scholar 

  46. J. Walker, S. Shadanbaz, N.T. Kirkland, E. Stace, T. Woodfield, M.P. Staiger, G.J. Dias, J. Biomed. Mater. Res. B 100, 1134 (2012)

    Article  Google Scholar 

  47. T. Li, Y. He, J. Zhou, S. Tang, Y. Yang, X. Wang, Mater. Lett. 217, 227 (2018)

    Article  CAS  Google Scholar 

  48. Y.S. Choi, J. Koo, J.A. Rogers, MRS Bull. 45(2), 103 (2020)

    Article  Google Scholar 

  49. L. Wang, C. Lu, S. Yang, P. Sun, Y. Wang, Y. Guan, S. Liu, D. Cheng, H. Meng, Q. Wang, J. He, H. Hou, H. Li, W. Lu, Y. Zhao, J. Wang, Y. Zhu, Y. Li, D. Luo, T. Li, H. Chen, S. Wang, X. Sheng, W. Xiong, X. Wang, J. Peng, L. Yin, Sci. Adv. 6(50), eabc6686 (2020). https://doi.org/10.1126/sciadv.abc6686

    Article  Google Scholar 

  50. D. Xue, Y. Yun, Z. Tan, Z. Dong, M.J. Schulz, J. Mater. Sci. Technol. 28, 261 (2012)

    Article  CAS  Google Scholar 

  51. P.K. Bowen, J. Drelich, J. Goldman, Adv. Mater. 25, 2577 (2013)

    Article  CAS  Google Scholar 

  52. X. Liu, H. Yang, Y. Liu, P. Xiong, H. Guo, H.H. Huang, Y. Zheng, JOM 71, 1414 (2019)

    Article  CAS  Google Scholar 

  53. J.J.D. Venezuela, S. Johnston, M.S. Dargusch, Adv. Healthc. Mater. 8, 1900408 (2019)

    Article  Google Scholar 

  54. J. Venezuela, M.S. Dargusch, Acta Biomater. 87, 1 (2019)

    Article  CAS  Google Scholar 

  55. V.S. Saji, C.W. Lee, ChemSusChem 5, 1146 (2012)

    Article  CAS  Google Scholar 

  56. K. Xu, S. Li, S. Dong, S. Zhang, G. Pan, G. Wang, L. Shi, W. Guo, C. Yu, J. Luo, Adv. Healthc. Mater. 8, 1801649 (2019)

    Article  Google Scholar 

  57. C. Dagdeviren, S.W. Hwang, Y. Su, S. Kim, H. Cheng, O. Gur, R. Haney, F.G. Omenetto, Y. Huang, J.A. Rogers, Small 9, 3398 (2013)

    Article  CAS  Google Scholar 

  58. X. Chen, S.M. Shinde, K.P. Dhakal, S.W. Lee, H. Kim, Z. Lee, J.H. Ahn, NPG Asia Mater. 10, 810 (2018)

    Article  CAS  Google Scholar 

  59. S.M. Yang, J.H. Shim, H.U. Cho, T.M. Jang, G.J. Ko, J. Shim, T.H. Kim, J. Zhu, S. Park, Y.S. Kim, S.Y. Joung, J.C. Choe, J.W. Shin, J.H. Lee, Y.M. Kang, H. Cheng, Y. Jung, C.H. Lee, D.P. Jang, S.W. Hwang, Adv. Mater. 34, 2108203 (2022)

    Article  CAS  Google Scholar 

  60. X. Chen, Y.J. Park, M. Kang, S.K. Kang, J. Koo, S.M. Shinde, J. Shin, S. Jeon, G. Park, Y. Yan, M.R. MacEwan, W.Z. Ray, K.M. Lee, J.A. Rogers, J.H. Ahn, Nat. Commun. 9, 1690 (2018)

    Article  Google Scholar 

  61. J.Y. Bae, E.J. Gwak, G.S. Hwang, H.W. Hwang, D.J. Lee, J.S. Lee, Y.C. Joo, J.Y. Sun, S.H. Jun, M.R. Ok, J.Y. Kim, S.K. Kang, Adv. Sci. 8, 2004029 (2021)

    Article  CAS  Google Scholar 

  62. X. Liu, M. Zhang, T. Xiao, J. Hao, R. Li, L. Mao, Anal. Chem. 88, 7238 (2016)

    Article  CAS  Google Scholar 

  63. H. Yuk, B. Lu, X. Zhao, Chem. Soc. Rev. 48, 1642 (2019)

    Article  CAS  Google Scholar 

  64. A. Tabet, M.J. Antonini, A. Sahasrabudhe, J. Park, D. Rosenfeld, F. Koehler, H. Yuk, S. Hanson, J. Stinson, M. Stok, X. Zhao, C. Wang, P. Anikeeva, ACS Cent. Sci. 7, 1516 (2021)

    Article  CAS  Google Scholar 

  65. S. Park, H. Yuk, R. Zhao, Y.S. Yim, E.W. Woldeghebriel, J. Kang, A. Canales, Y. Fink, G.B. Choi, X. Zhao, P. Anikeeva, Nat. Commun. 12, 3435 (2021)

    Article  CAS  Google Scholar 

  66. B. Zhu, S.C. Luo, H. Zhao, H.A. Lin, J. Sekine, A. Nakao, C. Chen, Y. Yamashita, H.H. Yu, Nat. Commun. 5, 4523 (2014)

    Article  CAS  Google Scholar 

  67. K.J. Yu, D. Kuzum, S.W. Hwang, B.H. Kim, H. Juul, N.H. Kim, S.M. Won, K. Chiang, M. Trumpis, A.G. Richardson, H. Cheng, H. Fang, M. Thomson, H. Bink, D. Talos, K.J. Seo, H.N. Lee, S.-K. Kang, J.-H. Kim, J.Y. Lee, Y. Huang, F.E. Jensen, M.A. Dichter, T.H. Lucas, J. Viventi, B. Litt, J.A. Rogers, Nat. Mater. 15(7), 782 (2016)

    Article  CAS  Google Scholar 

  68. D.-H. Kim, J. Viventi, J.J. Amsden, J. Xiao, L. Vigeland, Y-.S. Kim, J.A. Blanco, B. Panilaitis, E.S. Frechettte, D. Contreras, D.L. Kaplan, F.G. Omenetto, Y. Huang, K.-C. Hwang, M.R. Zakin, B. Litt, J.A. Rogers, Nat. Mater. 9(6), 511 (2010)

    Article  CAS  Google Scholar 

  69. M. Zhang, T. Desai, M. Ferrari, Biomaterials 19, 953 (1998)

    Article  CAS  Google Scholar 

  70. P. Zhang, L. Lin, D. Zang, X. Guo, M. Liu, Small 13, 1503334 (2017)

    Article  Google Scholar 

  71. M. Hedayati, M.M. Reynolds, D. Krapf, M.J. Kipper, ACS Appl. Mater. Interfaces 10(38), 31892 (2018)

    Article  CAS  Google Scholar 

  72. X. Liu, T. Xiao, F. Wu, M.Y. Shen, M. Zhang, H.H. Yu, L. Mao, Angew. Chem. 129, 11964 (2017)

    Article  Google Scholar 

  73. T. Feng, W. Ji, Y. Zhang, F. Wu, Q. Tang, H. Wei, M. Zhang, Angew. Chem. Int. Ed. 59, 23445 (2020)

    Article  CAS  Google Scholar 

  74. Y.S. Choi, R.T. Yin, A. Pfenniger, J. Koo, R. Avila, K.B. Lee, S.W. Chen, G. Lee, G. Li, Y. Qiao, A. Murillo-Berlioz, A. Kiss, S. Han, S.M. Lee, C. Li, Z. Xie, Y.Y. Chen, A. Burrell, B. Geist, H. Jeong, J. Kim, H.J. Yoon, A. Banks, S.K. Kang, Z.J. Zhang, C.R. Haney, A.V. Sahakian, D. Johnson, T. Efimova, Y. Huang, G.D. Trachiotis, B.P. Knight, R.K. Arora, I.R. Efimov, J.A. Rogers, Nat. Biotechnol. 39, 1228 (2021)

    Article  CAS  Google Scholar 

  75. C. Martin, T. Dejardin, A. Hart, M.O. Riehle, D.R. Cumming, Adv. Healthc. Mater. 3(7), 1001 (2013)

    Article  Google Scholar 

  76. J. Shin, Z. Liu, W. Bai, Y. Liu, Y. Yan, Y. Xue, I. Kandela, M. Pezhouh, M.R. MacEwan, Y. Huang, W.Z. Ray, W. Zhou, J.A. Rogers, Sci. Adv. 5(7), eaaw1899 (2019)

    Article  CAS  Google Scholar 

  77. S. Lee, J. Koo, S.K. Kang, G. Park, Y.J. Lee, Y.Y. Chen, S.A. Lim, K.M. Lee, J.A. Rogers, Mater. Today 21, 207 (2018)

    Article  CAS  Google Scholar 

  78. K.S. Kim, J. Yoo, J.S. Shim, Y.I. Ryu, S. Choi, J.Y. Lee, H.M. Lee, J. Koo, S.K. Kang, Adv. Mater. Technol. 7, 2001297 (2022)

    Article  CAS  Google Scholar 

  79. K.S. Kim, W.-Y. Maeng, S. Kim, G. Lee, M. Hong, G-.B. Kim, J. Kim, S. Kim, S. Han, J. Yoo, H. Lee, K. Lee, J. Koo, Mater. Today Bio 18, 100541 (2023)

    Article  CAS  Google Scholar 

  80. P. Chen, C. Xu, P. Wu, K. Liu, F. Chen, Y. Chen, Z. Luo, ACS Nano 16, 16513 (2022)

    Article  CAS  Google Scholar 

  81. J. Lee, H.R. Cho, G.D. Cha, H. Seo, S. Lee, C.K. Park, D.H. Kim, Nat. Commun. 10, 5205 (2019)

    Article  Google Scholar 

  82. J. Koo, S.B. Kim, Y.S. Choi, Z. Xie, A.J. Bandodkar, J. Khalifeh, Y. Yan, H. Kim, M.K. Pezhouh, K. Doty, G. Lee, Y.-Y. Chen, S.M. Lee, D. D'Andrea, K. Jung, K.H. Lee, K. Li, S. Jo, H. Wang, J.-H. Kim, J. Kim, S.-G. Choi, W.J. Jang, Y.S. Oh, I. Park, S.S. Kwak, J.-H. Park, D. Hong, X. Feng, C.-H. Lee, A. Banks, C. Leal, H.M. Lee, Y. Huang, C.K. Franz, W.Z. Ray, M. MacEwan, S.-K. Kang, J.A. Rogers, Sci. Adv. 6(35),eabb1093 (2020). https://doi.org/10.1126/sciadv.abb1093

    Article  Google Scholar 

  83. Y. Zhang, A.D. Mickle, P. Gutruf, L.A. McIlvried, H. Guo, Y. Wu, J.P. Golden, Y. Xue, J.G. Grajales-Reyes, X. Wang, S. Krishnan, Y. Xie, D. Peng, C.-J. Su, F. Zhang, J.T. Reeder, S.K. Vogt, Y. Huang, J.A. Rogers, R.W. Gereau IV, Sci. Adv. 5(7), eaaw5296 (2019). https://doi.org/10.1126/sciadv.aaw5296

    Article  Google Scholar 

Download references

Acknowledgments

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (Grant Nos. RS-2020KD000137, NRF2021K2A9A1A06086536) and the Korea Health Industry Development Institute (KHIDI) (Grant No. HI22C0647).

Author information

Authors and Affiliations

  1. School of Biomedical Engineering, College of Health Science, Korea University, Seoul, Republic of Korea

    Giheon Kim, Minki Hong, Yerim Lee & Jahyun Koo

  2. School of Biomedical Engineering, Interdisciplinary Program in Precision Public Health, Korea University, Seoul, Republic of Korea

    Giheon Kim, Minki Hong, Yerim Lee & Jahyun Koo

Authors
  1. Giheon Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Minki Hong
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yerim Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Jahyun Koo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jahyun Koo.

Ethics declarations

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kim, G., Hong, M., Lee, Y. et al. Biodegradable materials and devices for neuroelectronics. MRS Bulletin 48, 518–530 (2023). https://doi.org/10.1557/s43577-023-00529-0

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1557/s43577-023-00529-0

Keywords

Search

Navigation