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Biocompatible luminescent nanoparticles on the basis of calcium phosphate

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Abstract

Luminescent lanthanide doped SiO2/Hydroxylapatite (HAp) core/shell nanoparticles (NPs) were synthesized by sol-gel technology. The resulting NPs exhibited an amorphous SiO2 core and a crystalline luminescent shell. The formation of the HAp layer was possible at pH 8.5. The characterization of the resulting NPs was done by transmission electron microscopy, X-ray diffraction analysis, inductively-coupled plasma combined with optical emission spectrometry, and photoluminescence spectroscopy. Additionally, the newly developed SiO2/HAp:Ln3+ core/shell NPs were tested for their biocompatibility, e. g. by an in vitro cell culture based assay.

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Authors and Affiliations

  1. Fraunhofer Institute for Silicate Research ISC, Neunerplatz 2, Wuerzburg, 97082, Germany

    Sofia Dembski, Moritz Milde, Emeline Dassonneville & Carsten Gellermann

  2. Fraunhofer Institute for Molecular Biology and Applied Ecology, Forckenbeckstr. 6, Aachen, 52074, Germany

    Torsten Klockenbring

  3. Centre for Innovation Competence SiLi-nano®, Martin Luther University of Halle-Wittenberg, Karl-Freiherr-von-Fritsch-Str. 3, Halle, Saale, 06120, Germany

    Marcel Dyrba & Stefan Schweizer

  4. Fraunhofer Center for Silicon Photovoltaics, Walter-Hülse-Str. 1, Halle, Saale, 06120, Germany

    Stefan Schweizer

Authors
  1. Sofia Dembski
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  2. Moritz Milde
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  3. Emeline Dassonneville
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  4. Carsten Gellermann
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  5. Torsten Klockenbring
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  6. Marcel Dyrba
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  7. Stefan Schweizer
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Dembski, S., Milde, M., Dassonneville, E. et al. Biocompatible luminescent nanoparticles on the basis of calcium phosphate. MRS Online Proceedings Library 1355, 1113550504 (2011). https://doi.org/10.1557/opl.2011.1217

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  • DOI: https://doi.org/10.1557/opl.2011.1217

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