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From polydisperse diatomaceous earth to biosilica with specific morphologies by glucose gradient/dialysis: a natural material for cell growth

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Abstract

Starting from polydisperse diatomaceous earth (DE), we proposed an efficient separation method for obtaining different morphologies of bio-silica from diatoms. DE is a very low-cost source of silica containing all the differently nanostructured elements. By a glucose gradient/dialysis, three types of biosilica morphologies were achieved: rods, valves, and clusters. We fully characterized the diatom fractions and we used them to produce fluorescent biosilica platforms (“tabs”). These supports exhibited good resistance in water, ethanol, and soft scraping. A preliminary biologic application by testing Saos-2 proliferation was also performed to check osteoblasts-like cells biologic attitude for this scaffolds with tunable nanostructure.

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Authors and Affiliations

  1. CNR-ICCOM-Via Orabona, 4- 70125, Bari, Italy

    S. R. Cicco

  2. Università degli Studi di Bari «Aldo Moro», Via Orabona, 4- 70125, Bari, Italy

    D. Vona, G. Leone & M. Lo Presti

  3. CNR NANOTEC- Via Orabona, 4- 70125, Bari, Italy

    F. Palumbo

  4. Università degli Studi di Bari «Aldo Moro», Via Orabona, 4- 70125, Bari, Italy

    E. Altamura, R. Ragni & G. M. Farinola

Authors
  1. S. R. Cicco
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  2. D. Vona
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  3. G. Leone
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  4. M. Lo Presti
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  5. F. Palumbo
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  6. E. Altamura
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  7. R. Ragni
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  8. G. M. Farinola
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The supplementary material for this article can be found at https://doi.org/10.1557/mrc.2017.27

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Cicco, S.R., Vona, D., Leone, G. et al. From polydisperse diatomaceous earth to biosilica with specific morphologies by glucose gradient/dialysis: a natural material for cell growth. MRS Communications 7, 214–220 (2017). https://doi.org/10.1557/mrc.2017.27

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  • DOI: https://doi.org/10.1557/mrc.2017.27

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