Abstract
Microsporidiosis is considered to be emerging opportunistic infection in immunocompromised individuals worldwide. The aim of this study was to identify the specific serum antibodies to intestinal microsporidia Encephalitozoon cuniculi and Encephalitozoon intestinalis in women with Human Papillomavirus HPV and without HPV by the indirect immunofluorescence (IFA). From total number of 669 examined women, 225 were HPV positive and 444 women HPV negative. Overall the study comprised of 10.8% women with positive result for presence of E. cuniculi antibodies. In group 1 (HPV-positive women) it was more than 28% and in group 2 (HPV-negative women) it was less than 2% (p<0.001). E. intestinalis infection was found in total of 4.48% women, in group 1 it was present in less than 6% and in group 2 in less than 4% of women.
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Dascomb K., Frazer T., Clark R.A., Kissinger P., Didier E., 2000. Microsporidiosis and HIV. Journal of Acquired Immune Deficienty Syndromes, 24, 290–292
Didier P., Shadduck J. A. 1998. Modulated immune responsiveness associated with experimental Encephalitozoon cuniculi infection in BALB/c mice. Laboraory Animal Science, 38, 680–684
Franka R., Švrcek Š., Suli J., Beníšek Z., Madar M., Hipíková V., Levkutová M., Závadová J., Ondrejková A., Ondrejka R., Levkut M., Révajová V. 2006. Influence of Encephalitozoon cuniculi experimental infection on the antirabies immunity. Bulletin of the Veterinary Institute in Pulawy. 50, 309–313
Gissman L. 1997. Immunologic responses to human papillomavirus infection. Obstetrics Gynecology, 90, 7–11
Chalupský J., Vávra J., Bedrník P. 1973. Detection of antibodies to Encephalitozoon cuniculi in rabbits by the indirect immunofluorescent antibody test. Folia Parasitologica, 20, 281–284
Levkutová M., Revajová V., Levkut M. 1998. Subpopulations of lymphocytes in cattle naturally infected with papillomavirus. Acta Veterinaria Hungarica, 46, 13–18
Mohanty K.C., Roy R.V. 1984. Thymus derived lymphocyte (T-cells) in patients with genital warts. Br. Journal of Veneral Disease, 60, 186–188
Moretto M., Durrel B., Khan A.I., Casicotti L. 2000. Lack of CD4+ T cells does not affect induction of CD8 T cell immunity against Encephalitozoon cuniculi infection, Infection & Immunity, 68, 6223–6232
Moretto M., Weiss L.M., Khan I.A. 2004. Induction of a rapid and strong antigen-specific intraepithelial lymphocyte response during oral Encephalitozoon cuniculi infection, Journal of Immunology, 172, 4402–4409
Orenstein J.M. 2003. Diagnostic pathology of microsporidiosis. Ultrastructural Pathology, 27, 141–149
Shearer G.M., Berstein C.D., Tung S.K., Via C.S., Redfield R., Salahuddin S.Z., Gallo R.C. 1986. A model for selective loss of major histocompatibility complex self restricted T cell immune response during the development of acquired immune deficiency syndrome (AIDS). Journal of Immunology, 137, 2514–2521
Valencakova A., Balent P., Malcekova B., Lesnik F., Halanova M., Hipikova V. 2002. Comparison of mammalian microsporidia species replication in various cell lines. Biologia, 57, 773–776
Valencakova A., Revajova V., Bálent P., Lešník F., Levkut M. 2003. Immunosuppressive effect of Encephalitozoon cuniculi. Bulletin of the Veterinary Institute in Pulawy. 47, 113–120
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Adam, J., Valenčáková, A., Halánová, M. et al. Serological screening of selected microsporidia in HPV-positive women. Acta Parasit. 60, 50–53 (2015). https://doi.org/10.1515/ap-2015-0007
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DOI: https://doi.org/10.1515/ap-2015-0007