Abstract
Ever since Professor William T. Creasman suggested the use of hormone replacement therapy in breast cancer survivors in the early 1980s, interest in this field has been guarded but present. Prescribing HRT to breast cancer survivors was initially thought of as being outrageous. Yet even then with experience in HRT spanning a good three decades, and with the breast cancer epidemic, so confidently predicted, then as it is now never actually materializing, doctors working in the field had started to question the conventional wisdom. The debate on whether to treat breast cancer survivors with HRT has been revisited from time to time as there has been a powerful demand for a solution for such symptomatic women. The HABITS study was thus designed to investigate the use of HRT in breast cancer survivors.
Similar content being viewed by others
References
Colditz, G., Egan, W., and Stampfer, M. J. (1993). Am. J. Obstet. Gynaecol. 168, 1473–1480.
Biglia, N., Cozzorella, M., Cecciari, F., et al. (2003). Maturitas 45, 29–38.
Holmberg, L. and Anderson, H., for the HABITS Steering and Data Monitoring committees. (2004). Lancet 363, 453–455.
O’Meara, E., Rossing, M., Daling, J., et al. (2001). J. Natl. Cancer Inst. 93, 754–762.
Sellers, T., Mink, P. Certam, J., et al. (1997). Ann. Intern. Med. 127, 973–980.
Durna, E., Wren, B., Heller, G., et al. (2002). Med. J. Aust. 177, 347–351.
Wren, B. (1993). Bailliere Clin. Endocrinol. Metab. 7, 225–242.
Bluming, V., Waishman, J., Doski, G., et al. Presented at the 18th meeting of the American Society of Clinical Oncology, p. 471.
Brewster, W., DiSaia, P., Grosen, E. A., et al. (1999). Int. J. Fertil. 44, 186–192.
DiSaia, P., Brewster, W., Zoogas, A., et al. (1985). J. Steroid Biochem. 23, 111–113.
Toma, S., Leonessa, F., Coialbo, T., et al. (1985). Anticancer Res. 9, 303–308.
Dew, J., Wren, B., and Eden, J. (2002). Climacteric 5, 151–155.
Creasman, W. and Wohler, M. In: The management of the menopause. Studd, J. (ed.). Chapter 9, pp. 78–83.
American College of Obstetricians & Gynaecologists Committee Opinion. Number 226, November 1999, Washington, DC.
Guidelines for the Hormone Treatment of Women in the Menopausal Transition and Beyond. Position statement by the Executive Committee of the International Menopause Society. February 13, 2004.
Rylander-Rudqvist, T., Wedra, S., Graneth, R., et al. (2003). Carcinogenesis 24, 1533–1539.
Rights and permissions
About this article
Cite this article
Brincat, M., Baron, Y.M. & Ciantar, E. Hormone replacement in women with breast cancer. Endocr 24, 255–257 (2004). https://doi.org/10.1385/ENDO:24:3:255
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1385/ENDO:24:3:255