Abstract
Metallic tin powder injected into Lewis rats caused marked enlargement of draining lymph nodes with prominent hyperplasia of plasma cells. A low level of dietary protein (8%) or deficiency of choline interfered with the cellular proliferation and reduced the size of the nodes by nearly onethird compared to a normal protein diet (20%). A high level of protein in the diet (50%) did not augment the effect of metallic tin powder beyond that achieved by a level usually considered adequate (20%).
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Levine, S., Saltzman, A. Malnutrition interferes with the unique lymphadenopathy induced in lewis rats by metallic tin. Biol Trace Elem Res 85, 71–76 (2002). https://doi.org/10.1385/BTER:85:1:71
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DOI: https://doi.org/10.1385/BTER:85:1:71