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Chiral tetrahedral complex catalyzing asymmetric addition of diethylzinc to benzaldehyde

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Abstract

The optical active alkyne-bridged Mo-Co heterometal complexes are synthesized by the chiral phase transfer catalyst (N-benzylcinchorin chloride) induced metal exchange reaction. The complex is used as catalyst to promote the asymmetric addition of diethylzinc to benzaldehyde. The ee value of the product alcohol is 5.7%, which illustrates the asymmetric induction of the tetrahedral framework chirality in asymmetric catalysis reaction for the first time.

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Authors and Affiliations

  1. State Key Laboratory for Oxo Synthesis and Selective Oxidation, Chinese Academy of Sciences, 730000, Lanzhou, China

    Weiqiang Zhang & Yuanqi Yin

  2. Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 730000, Lanzhou, China

    Xiaoqian Han & Liren Chen

Authors
  1. Weiqiang Zhang
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  2. Yuanqi Yin
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  3. Xiaoqian Han
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  4. Liren Chen
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Correspondence to Yuanqi Yin.

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Zhang, W., Yin, Y., Han, X. et al. Chiral tetrahedral complex catalyzing asymmetric addition of diethylzinc to benzaldehyde. Sc. China Ser. B-Chem. 45, 481–487 (2002). https://doi.org/10.1360/02yb9063

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  • DOI: https://doi.org/10.1360/02yb9063

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